184174-80-9

Basic information

• Product Name: 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER
• Synonyms: ART-CHEM-BB B000471;METHYL 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLATE;2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER;4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID, 2-AMINO-5,6-DIHYDRO-, METHYL ESTER;AKOS B000471;AKOS BBB/008;4H-Cyclopenta[b]thiophene-3-carboxylicacid,2-amino-5,6-dihydro-,methyl;2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIO
• CAS NO: 184174-80-9
• Molecular Formula: C₉H₁₁NO₂S
• Molecular Weight: 197.25
• Product Categories: AMINOACID;Thiophene
• Mol File: 184174-80-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 177°C
• Boiling Point: 378.6±42.0 °C at 760 mmHg
• Flash Point: 182.8±27.9 °C
• Appearance: /
• Density: 1.3±0.1 g/cm³
• Vapor Pressure: 6.2E-06mmHg at 25°C
• Refractive Index: 1.631
• Storage Temp.: 2-8°C
• PKA: 0.52±0.20(Predicted)
• CAS DataBase Reference: 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(184174-80-9)
• EPA Substance Registry System: 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER(184174-80-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 184174-80-9(Hazardous Substances Data)

Usage

Description

2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER, also known as Methyl 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate, is a grey solid intermediate compound that plays a significant role in the synthesis of azo thiophene disperse dyes. Its unique chemical structure and properties make it a valuable component in the production of various dyes used in different industries.

Uses

Used in Textile Industry:
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER is used as an intermediate in the synthesis of azo thiophene disperse dyes for the textile industry. Its role in creating vibrant and long-lasting colors in fabrics is essential, contributing to the aesthetic appeal and durability of textile products.
Used in Plastics and Polymer Industry:
In the plastics and polymer industry, 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER is used as an intermediate for the development of azo thiophene disperse dyes that can be applied to plastics and polymers. These dyes enhance the visual appeal and colorfastness of the final products, making them more attractive and resistant to fading.
Used in Printing and Packaging Industry:
2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER is also utilized in the printing and packaging industry as an intermediate for azo thiophene disperse dyes. These dyes are crucial for producing high-quality, vibrant, and long-lasting prints on various packaging materials, ensuring that the final products are visually appealing and resistant to color degradation.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 2-AMINO-5,6-DIHYDRO-4H-CYCLOPENTA[B]THIOPHENE-3-CARBOXYLIC ACID METHYL ESTER, due to its unique chemical structure, may also have potential applications in the pharmaceutical industry. It could be used as a building block for the development of new drugs or as an intermediate in the synthesis of various pharmaceutical compounds. Further research and development would be required to explore these possibilities.

InChI:InChI=1/C9H11NO2S/c1-12-9(11)7-5-3-2-4-6(5)13-8(7)10/h2-4,10H2,1H3

Upstream product

• 67-56-1 methanol 
• 372-09-8 cyanoacetic acid 
• 120-92-3 cyclopentanone 
• 105-34-0 methyl 2-cyanoacetate 

Downstream Products

• 1268706-70-2 C₁₆H₁₈N₂O₃S 
• 1268706-83-7 C₁₉H₁₈N₂O₅S 
• 1268706-96-2 C₂₅H₂₂FN₃O₄S 
• 1268707-07-8 C₁₇H₁₄FN₃O₃S 
• 1240504-50-0 methyl 2-[(1-benzyl-5-oxo-4-trifluoromethyl-2-phenyl-4,5-dihydroimidazol-4-yl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate 

Relevant articles and documents

Microwave-assisted synthesis of 2-aminothiophene derivatives via improved gewald reactions

In this paper, a new and efficient method was developed to prepare 2-aminothiophene derivatives through improved Gewald reaction. Thirty-one final products were synthesized under microwave radiation for 30 min with 57%-95% isolated yields. All the product

SULFONYLUREA DERIVATIVES AND USES THEREOF

The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.

Azo dyes

The azo dyes relate to thiophene azo dyes of the general formula: where R1 is Cyano or C1-C5 alkoxy carbonyl; R2 is hydrogen, halogene, C1-C2 alkyl, phenyl, or substituted phenyl; and R3 is C1-C5 alkoxy carbonyl, C1-C4 alkanoyl, benzoyl, phenyl, alkyl substituted phenyl, or alkoxy phenyl; or R2 and R3 are fused cycloalkane with C3-C5.