184296-13-7

Basic information

• Product Name: (5S,8S,11R,14S,17R,20S,22aS)-5,11-Dibenzyl-20-((S)-1-hydroxy-ethyl)-8,14-bis-hydroxymethyl-17-isopropyl-hexadecahydro-3a,6,9,12,15,18,21-heptaaza-cyclopentacyclohenicosene-4,7,10,13,16,19,22-heptaone
• Synonyms: (5S,8S,11R,14S,17R,20S,22aS)-5,11-Dibenzyl-20-((S)-1-hydroxy-ethyl)-8,14-bis-hydroxymethyl-17-isopropyl-hexadecahydro-3a,6,9,12,15,18,21-heptaaza-cyclopentacyclohenicosene-4,7,10,13,16,19,22-heptaone
• CAS NO: 184296-13-7
• Molecular Weight: 765.864
• Mol File: 184296-13-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5S,8S,11R,14S,17R,20S,22aS)-5,11-Dibenzyl-20-((S)-1-hydroxy-ethyl)-8,14-bis-hydroxymethyl-17-isopropyl-hexadecahydro-3a,6,9,12,15,18,21-heptaaza-cyclopentacyclohenicosene-4,7,10,13,16,19,22-heptaone(CAS DataBase Reference)
• NIST Chemistry Reference: (5S,8S,11R,14S,17R,20S,22aS)-5,11-Dibenzyl-20-((S)-1-hydroxy-ethyl)-8,14-bis-hydroxymethyl-17-isopropyl-hexadecahydro-3a,6,9,12,15,18,21-heptaaza-cyclopentacyclohenicosene-4,7,10,13,16,19,22-heptaone(184296-13-7)
• EPA Substance Registry System: (5S,8S,11R,14S,17R,20S,22aS)-5,11-Dibenzyl-20-((S)-1-hydroxy-ethyl)-8,14-bis-hydroxymethyl-17-isopropyl-hexadecahydro-3a,6,9,12,15,18,21-heptaaza-cyclopentacyclohenicosene-4,7,10,13,16,19,22-heptaone(184296-13-7)

Safety Data

• Hazardous Substances Data: 184296-13-7(Hazardous Substances Data)

Upstream product

• 1685-33-2 N-[(benzyloxy)carbonyl]-D-valine 
• 184295-92-9 (2S,3R)-2-{[(S)-1-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-hydroxy-butyric acid methyl ester 
• 184295-93-0 (2S,3S)-2-{[(S)-1-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionyl)-pyrrolidine-2-carbonyl]-amino}-3-hydroxy-butyric acid methyl ester 
• 102988-92-1 C₂₇H₃₂N₂O₇ 
• 41445-88-9 (2-methylpropoxy)carbonyl N-[(benzyloxy)carbonyl]-D-valinate 
• 7669-64-9 (2S)-1-((2S)-2-[[(benzyloxy)carbonyl]amino]-3-phenylpropanoyl)tetrahydro-1H-pyrrole-2-carboxylic acid 
• 28426-51-9 methyl ((benzyloxy)carbonyl)-L-phenylalanyl-L-prolinate 
• 41518-17-6 C₂₂H₂₅NO₆ 
• 41518-17-6 Z-Phe-O-COO-isoBu 
• 2448-45-5 Cbz-D-Phe 
• 63655-58-3 Z-D-Phe-Ser-OMe 
• 1161-13-3 N-Cbz-L-Phe 
• 184296-07-9 (5S,8S,11R,14S,17R,20S,22aS)-5,11-Dibenzyl-8,14-bis-(tert-butyl-dimethyl-silanyloxymethyl)-20-((S)-1-hydroxy-ethyl)-17-isopropyl-hexadecahydro-3a,6,9,12,15,18,21-heptaaza-cyclopentacyclohenicosene-4,7,10,13,16,19,22-heptaone 
• 184295-97-4 Cbz-D-Val-Ser(TBDMS)-D-Phe-Ser(TBDMS)-Phe-Pro-allo-Thr-OMe 

Downstream Products

• 184296-00-2 cyclo[D-Val-Ser(oxaz)-D-Phe-Ser(oxaz)-Phe-Pro-Allo-Thr(oxaz)] 

Relevant articles and documents

Total synthesis and assignment of configuration of lissoclinamide 7

The first total synthesis of lissoclinamide 7, a 21-membered cyclopeptide isolated from Lissoclinum bistratum, was accomplished in 23 steps and 4.4% overall yield. The extraordinary configurational lability of the thiazoline segments was overcome by a novel strategy combining the use of the Burgess reagent for multiple simultaneous oxazoline and thiazoline formations and an efficient oxazoline → thiazoline heterocycle interconversion. In addition to the total synthesis, this work highlights the scope of alternative strategies toward Lissoclinum peptides and presents the preparation of analogues for SAR studies of the cytotoxic effects of this family of marine natural products.