184297-12-9

Basic information

• Product Name: Toluene-4-sulfonic acid (2R,3R,5S)-2-(6-amino-purin-9-yl)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester
• Synonyms: Toluene-4-sulfonic acid (2R,3R,5S)-2-(6-amino-purin-9-yl)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester
• CAS NO: 184297-12-9
• Molecular Weight: 519.697
• Mol File: 184297-12-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Toluene-4-sulfonic acid (2R,3R,5S)-2-(6-amino-purin-9-yl)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Toluene-4-sulfonic acid (2R,3R,5S)-2-(6-amino-purin-9-yl)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester(184297-12-9)
• EPA Substance Registry System: Toluene-4-sulfonic acid (2R,3R,5S)-2-(6-amino-purin-9-yl)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester(184297-12-9)

Safety Data

• Hazardous Substances Data: 184297-12-9(Hazardous Substances Data)

Upstream product

• 42776-78-3 2'-O-tosyladenosine 
• 98-59-9 p-toluenesulfonyl chloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 115094-43-4 5'-O-(tert-butyldimethylsilyl)-2'-O-(p-tolylsulfonyl)adenosine 
• 69304-45-6 3',5'-O-(1,1,3,3-tetra-isopropyldisiloxane-1,3-diyl)adenosine 
• 184297-07-2 Toluene-4-sulfonic acid (2R,3R,4R,5R)-2-(6-amino-purin-9-yl)-5-(tert-butyl-dimethyl-silanyloxymethyl)-4-phenoxythiocarbonyloxy-tetrahydro-furan-3-yl ester 

Relevant articles and documents

Nucleic acid related compounds. 91. Biomimetic reactions are in harmony with loss of 2'-substituents as free radicals (not anions) during mechanism-based inactivation of ribonucleotide reductases. Differential interactions of azide, halogen, and alkylthio

The initial step in the mechanism-based inactivation of ribonucleotide reductases by 2'-chloro-2'deoxynucleotides is abstraction of H3' by a proximal free radical on the enzyme. The C3' radical is postulated to undergo spontaneous loss of chloride, and th