18430-02-9

Basic information

• Product Name: 3-carboxy-4-nitrobenzenethiolate
• CAS NO: 18430-02-9
• Molecular Weight: 198.179
• Mol File: 18430-02-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-carboxy-4-nitrobenzenethiolate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-carboxy-4-nitrobenzenethiolate(18430-02-9)
• EPA Substance Registry System: 3-carboxy-4-nitrobenzenethiolate(18430-02-9)

Safety Data

• Hazardous Substances Data: 18430-02-9(Hazardous Substances Data)

Upstream product

• 69-78-3 5,5'-dithiobis-(2-nitrobenzoic acid) 
• 74-90-8 hydrogen cyanide 
• 6186-89-6 ethyl methyl malonate 
• 20733-16-8 n-butyl mercaptyl anion 
• 597-82-0 O,O,O-triphenyl phosphorothioate 
• 134257-67-3 octanethiolate 
• 29869-27-0 naphthalene-2-thiolate 
• 16136-29-1 2-Amino-2-carboxy-ethanethiol anion 
• 40055-99-0 2-(4-Amino-4-carboxy-butyrylamino)-2-(carboxymethyl-carbamoyl)-ethanethiol anion 
• 13133-62-5 thiophenolate 
• 79-46-9 2-nitropropane 
• 75-52-5 nitromethane 
• 79-24-3 Nitroethane 
• 4468-05-7 acetylthiocholine 

Relevant articles and documents

Reactivity Control in Micelles and Surfactant Vesicles. Kinetics and Mechanism of Base-Catalyzed Hydrolysis of 5,5'-Dithiobis(2-nitrobenzoic acid) in Water, Hexadecyltrimethylammonium Bromide Micelles, and Dioctadecyldimethylammonium Chloride Surfactant V

Rate constants have been determined for the hydrolysis of 5,5'-dithiobis(2-nitrobenzoic acid) (DTNB) as functions of hydroxide ion concentrations in water, micellar hexadecyltrimethylammonium bromide (CTAB), and dioctadecyldimethylammonium chloride (DODAC

Synthesis and investigation of inhibitory activities of imidazole derivatives against the metallo-β-lactamase IMP-1

Mutations in bacteria can result in antibiotic resistance due to the overuse or abuse of β-lactam antibiotics. One strategy which bacteria can become resistance toward antibiotics is secreting of metallo β-lactamase enzymes that can open the lactam ring of the β-lactam antibiotic and inactivate them. This issue is a threat for human health and one strategy to overcome this situation is co-administration of β-lactam antibiotics with an inhibitor. So far, no clinically available inhibitors of metallo β-lactamases (MBLs) reported and the clinically inhibitors of serine β-lactamase are useless for MBLs. Accordingly, finding a potent inhibitor of the MBLs being very important. In this study, imidazole derivatives primarily were synthesized and their inhibitory activity were measured. Later in silico binding model was used to predict the configuration and conformation of the ligands into the active site of enzyme. Two molecules demonstrated with IC50 of 39 μM and 46 μM against MBL (IMP-1).

Tandem driven dynamic self-inhibition of acetylcholinesterase

A concept of tandem driven dynamic self-inhibition is demonstrated through dynamic inhibitors of acetylcholinesterase (AChE) using reversible transthiolesterification.