184354-37-8Relevant articles and documents
Facile and rapid access to linear and truncated microcystin analogues for the implementation of immunoassays
Clave,Ronco,Boutal,Kreich,Volland,Franck,Romieu,Renard
experimental part, p. 676 - 690 (2010/05/02)
A series of simplified microcystin-LR analogues based on Adda [(2S,3S,8S,9S,4E,6E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldecadienoic acid] or its corresponding aldol precursor linked to a polypeptide moiety have been synthesised and assessed for thei
Total synthesis of the serine-threonine phosphatase inhibitor microcystin-LA
Humphrey, John M.,Aggen, James B.,Chamberlin, A. Richard
, p. 11759 - 11770 (2007/10/03)
Reversible protein phosphorylation, which is mediated by kinases and phosphatases, is a major control element of the cell. There is a diverse group of toxic natural products that inhibit certain phosphatases, thereby disrupting normal biochemical pathways