184357-24-2

Basic information

• Product Name: [(1S,2R)-1-Benzyl-3-(cyclohexylmethyl-amino)-2-hydroxy-propyl]-carbamic acid benzyl ester
• Synonyms: [(1S,2R)-1-Benzyl-3-(cyclohexylmethyl-amino)-2-hydroxy-propyl]-carbamic acid benzyl ester
• CAS NO: 184357-24-2
• Molecular Weight: 410.557
• Mol File: 184357-24-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(1S,2R)-1-Benzyl-3-(cyclohexylmethyl-amino)-2-hydroxy-propyl]-carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(1S,2R)-1-Benzyl-3-(cyclohexylmethyl-amino)-2-hydroxy-propyl]-carbamic acid benzyl ester(184357-24-2)
• EPA Substance Registry System: [(1S,2R)-1-Benzyl-3-(cyclohexylmethyl-amino)-2-hydroxy-propyl]-carbamic acid benzyl ester(184357-24-2)

Safety Data

• Hazardous Substances Data: 184357-24-2(Hazardous Substances Data)

Upstream product

• 128018-43-9 N-benzyloxycarbonyl-3(S)-amino-1-chloro-4-phenyl-2(S)-butanol 
• 26049-94-5 (S)-benzyl (4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate 
• 128018-44-0 N-benzyloxycarbonyl-3(S)-amino-1,2(S)epoxy-4-phenylbutane 
• 3218-02-8 cyclohexylmethylamine 

Downstream Products

• 148245-99-2 {(S)-1-[(1S,2R)-1-Benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propylcarbamoyl]-2-carbamoyl-ethyl}-carbamic acid benzyl ester 
• 1053748-44-9 (S)-2-Amino-N¹-[(1S,2R)-1-benzyl-3-(3-tert-butyl-1-cyclohexylmethyl-ureido)-2-hydroxy-propyl]-succinamide 
• 1055033-75-4 1-((2R,3S)-3-Amino-2-hydroxy-4-phenyl-butyl)-3-tert-butyl-1-cyclohexylmethyl-urea 

Relevant articles and documents

Succinoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors

Succinoylamino hydroxyethylamino sulfonyl urea derivatives of the formula: wherein the substituents are as defined in the specification, are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.

Discovery of a Novel Class of Potent HIV-1 Protease Inhibitors Containing the (R)-(Hydroxyethyl)urea Isostere

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