184867-89-8Relevant articles and documents
New strategy for the synthesis of the taxane diterpenes: Formation of the BC-rings of taxol via a [5+2]-pyrylium ylide-alkene cyclization, ring expansion strategy
Bauta, William,Booth, John,Bos, Mary Ellen,DeLuca, Mark,Diorazio, Louis,Donohoe, Timothy,Magnus, Nicholas,Magnus, Philip,Mendoza, Jose,Pye, Philip,Tarrant, James,Thom, Stephen,Ujjainwalla, Feroze
, p. 5327 - 5330 (1995)
The BC-rings of taxol can be synthesized using an intramolecular [5+2]- pyrylium ylide-alkene cyclization, followed by gem-methylcyclopropanation and reductive cleavage of the internal cyclopropane bond.