18498-01-6 Usage
Description
[1,2-Bis(diphenyphosphino)ethane]dichlorocobalt(II) is a cobalt-based organometallic compound featuring a complex structure with diphenylphosphino groups attached to an ethane backbone. [1,2-Bis(diphenyphosphino)ethane]dichlorocobalt(II) is known for its catalytic properties and is widely utilized in various chemical reactions due to its ability to facilitate selective transformations.
Uses
Used in Chemical Synthesis:
[1,2-Bis(diphenyphosphino)ethane]dichlorocobalt(II) is used as a catalyst for promoting regioand stereoselective intermolecular enzyme coupling. This application is crucial in the synthesis of complex organic molecules with specific structural requirements, ensuring that the desired product is formed with high selectivity and minimal side reactions.
Used in Cross-Coupling Reactions:
In the field of organic chemistry, this cobalt compound is employed as a catalyst for cross-coupling reactions of alkyl halides with aryl Grignard reagents. These reactions are essential for constructing carbon-carbon bonds, which are the backbone of many organic molecules, including pharmaceuticals and natural products.
Used in Hydrovinylation of Styrene:
[1,2-Bis(diphenyphosphino)ethane]dichlorocobalt(II) is utilized as a catalyst in the hydrovinylation of styrene, a process that involves the addition of a hydrogen atom and an alkene group across a double bond. This reaction is significant in the production of various industrial chemicals and polymers.
Used in Tandem Radical Cyclization and Cross-Coupling:
The compound is also used as a catalyst in tandem radical cyclization and cross-coupling reactions, which are vital for constructing complex molecular architectures and natural product synthesis. These reactions allow for the formation of multiple bonds and rings in a single operation, streamlining the synthesis process.
Used in Dimethylation Reactions:
As a catalyst, [1,2-Bis(diphenyphosphino)ethane]dichlorocobalt(II) is employed in dimethylation reactions, where it facilitates the introduction of two methyl groups into a molecule. This is an important transformation in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.
Used in Hydrodechlorination and Addition Reactions:
Lastly, this cobalt compound is used as a catalyst in hydrodechlorination and addition reactions, where it aids in the removal of chlorine atoms from organic molecules and the addition of other functional groups. These reactions are essential for the synthesis of various chemicals and the modification of existing molecules to improve their properties or reactivity.
Reactions
Catalyst used for the hydrovinylation of styrene.
Cobalt-catalyzed hydroalkylation of [60] fullerene with active alkyl bromides.
Cobalt-catalyzed 1,4-addition of organoboronic acids to activated alkenes.
Check Digit Verification of cas no
The CAS Registry Mumber 18498-01-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,4,9 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18498-01:
(7*1)+(6*8)+(5*4)+(4*9)+(3*8)+(2*0)+(1*1)=136
136 % 10 = 6
So 18498-01-6 is a valid CAS Registry Number.
InChI:InChI=1/C26H24P2.2ClH.Co/c1-5-13-23(14-6-1)27(24-15-7-2-8-16-24)21-22-28(25-17-9-3-10-18-25)26-19-11-4-12-20-26;;;/h1-20H,21-22H2;2*1H;/q;;;+2/p-2
18498-01-6Relevant articles and documents
Homogeneous Electrochemical Reduction of CO2 to CO by a Cobalt Pyridine Thiolate Complex
Ahmed, Md Estak,Dey, Abhishek,Dey, Subal,Rana, Atanu,Saha, Rajat
supporting information, p. 5292 - 5302 (2020/04/20)
The chemical and electrochemical reduction of CO2 to value added chemicals entails the development of efficient and selective catalysts. Synthesis, characterization and electrochemical CO2 reduction activity of a air-stable cobalt(III) diphenylphosphenethano-bis(2-pyridinethiolate)chloride [{Co(dppe)(2-PyS)2}Cl, 1-Cl] complex is divulged. The complex reduces CO2 under homogeneous electrocatalytic conditions to produce CO with high Faradaic efficiency (FE > 92%) and selectivity in the presence of water. Through detailed electrochemical investigations, product analysis, and mechanistic investigations supported by theoretical calculations, it is established that complex 1-Cl reduces CO2 in its Co(I) state. A reductive cleavage leads to a dangling protonated pyridine arm which enables facile CO2 binding through a H-bond donation and facilitates the C-O bond cleavage via a directed protonation. A systematic benchmarking of this catalyst indicates that it has a modest overpotential (～180 mV) and a TOF of ～20 s-1 for selective reduction of CO2 to CO with H2O as a proton source.
Cobalt-catalysed asymmetric hydrovinylation of 1,3-dienes
Timsina, Yam N.,Sharma, Rakesh K.,Rajanbabu
, p. 3994 - 4008 (2015/06/25)
In the presence of bidentate 1,n-bis-diphenylphosphinoalkane-CoCl2 complexes {Cl2Co[P ～ P]} and Me3Al or methylaluminoxane, acyclic (E)-1,3-dienes react with ethylene (1 atmosphere) to give excellent yields of hydrovinylat
