18505-71-0

Basic information

• Product Name: Benzenamine, N-[(4,5-dimethoxy-2-nitrophenyl)methylene]-4-methyl-
• CAS NO: 18505-71-0
• Molecular Formula: C16H16N2O4
• Molecular Weight: 300.314
• Mol File: 18505-71-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenamine, N-[(4,5-dimethoxy-2-nitrophenyl)methylene]-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N-[(4,5-dimethoxy-2-nitrophenyl)methylene]-4-methyl-(18505-71-0)
• EPA Substance Registry System: Benzenamine, N-[(4,5-dimethoxy-2-nitrophenyl)methylene]-4-methyl-(18505-71-0)

Safety Data

• Hazardous Substances Data: 18505-71-0(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 20357-25-9 6-nitroveratraldehyde 
• 106-49-0 p-toluidine 

Downstream Products

• 350249-75-1 ethyl 2-{[N((S)-1-hydroxy-3-phenyl)prop-2-yl]-3-aminopropyl}-6,7-dimethoxyquinoline-3-carboxylate 
• 350249-77-3 2-[(S)-1-hydroxy-3-phenylprop-2-yl]-2,3,4,5-tetrahydro-8,9-dimethoxyazepino[4,3-b]quinolin-1-one 
• 597585-09-6 ethyl 6,7-dimethoxy-2-phenyl-3-quinolinecarboxylate 

Relevant articles and documents

A novel traceless solid-phase Friedlaender synthesis

(Matrix presented) A new solid-phase synthesis of quinolines based on a Friedlaender-type reaction between the resin-bound azomethine 1b and ketones 2 is described. This cyclative cleavage approach affords quinolines 3a-f in 50-81% yields. The polymer-bou

Synthesis and bioevaluation of 22-hydroxyacuminatine analogs

A series of 22-hydroxyacuminatine analogs was prepared by using different Friedlaender condensations. Several of the new compounds were tested for antiproliferative activity on cancer cell lines and for topoisomerase I inhibitory activity.