185146-84-3

Basic information

• Product Name: BOC-L-2-NITROPHENYLALANINE
• Synonyms: BOC-PHE(2-NO2)-OH;BOC-L-PHE(2-NO2);BOC-2-NITRO-L-PHENYLALANINE;BOC-L-2-NITROPHE;BOC-L-2-NITROPHENYLALANINE;(S)-N-ALPHA-T-BUTOXYCARBONYL-2-AMINO-3-(2-NITRO-PHENYL)-PROPANOIC ACID;2-Nitro-L-phenylalanine, N-BOC protected;(S)-2-(tert-butoxycarbonylamino)-3-(2-nitrophenyl)propanoic acid
• CAS NO: 185146-84-3
• Molecular Formula: C₁₄H₁₈N₂O₆
• Molecular Weight: 310.3
• Product Categories: Amino Acids;Phenylalanine analogs and other aromatic alpha amino acids
• Mol File: 185146-84-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 488 °C at 760 mmHg
• Flash Point: 248.934 °C
• Appearance: Off-white powder
• Density: 1.29 g/cm³
• Vapor Pressure: 2.45E-10mmHg at 25°C
• Refractive Index: 1.553
• Storage Temp.: Store at R.T.
• CAS DataBase Reference: BOC-L-2-NITROPHENYLALANINE(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-L-2-NITROPHENYLALANINE(185146-84-3)
• EPA Substance Registry System: BOC-L-2-NITROPHENYLALANINE(185146-84-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 185146-84-3(Hazardous Substances Data)

Usage

Description

BOC-L-2-NITROPHENYLALANINE is a protected derivative of L-Phenylalanine, an essential amino acid that plays a crucial role in various biological processes. It is characterized by its off-white powder form and is primarily used in the photocleavage of polypeptide backbones, which is significant in the field of molecular biology and biochemistry.

Uses

Used in Molecular Biology:
BOC-L-2-NITROPHENYLALANINE is used as a photocleavage agent for polypeptide backbones, enabling the manipulation and study of proteins and their interactions within biological systems. This application is vital for understanding protein structures, functions, and roles in cellular processes.
Used in Biochemistry:
As a derivative of L-Phenylalanine, BOC-L-2-NITROPHENYLALANINE is used in the study of amino acid metabolism and its conversion into other essential compounds such as L-tyrosine, L-DOPA, dopamine, norepinephrine, and epinephrine. These conversions are crucial for various physiological functions, including the synthesis of neurotransmitters and hormones.
Used in Pharmaceutical Research:
BOC-L-2-NITROPHENYLALANINE serves as a valuable compound in the development of new drugs targeting the L-Phenylalanine metabolic pathway. Its role in the synthesis of neurotransmitters and hormones makes it a potential candidate for the treatment of various neurological and endocrine disorders.
Used in Chemical Synthesis:
BOC-L-2-NITROPHENYLALANINE is utilized as a building block in the synthesis of complex organic molecules, particularly those involving the L-Phenylalanine backbone. This application is essential in the development of novel compounds with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C14H18N2O6/c1-14(2,3)22-13(19)15-10(12(17)18)8-9-6-4-5-7-11(9)16(20)21/h4-7,10H,8H2,1-3H3,(H,15,19)(H,17,18)/t10-/m1/s1

Relevant articles and documents

NITRATION

The present invention relates to a process for preparing a nitrated compound, comprising the step of reacting a compound (A) comprising at least one substituted or unsubstituted aromatic or heteroaromatic ring, wherein said heteroaromatic ring comprises at least one heteroatom selected from the group consisting of oxygen, sulfur, phosphor, selenium and nitrogen, with a compound of formula (I) wherein Y is selected from the group consisting of hydrogen and nitro.