185387-36-4

Basic information

• Product Name: (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID
• Synonyms: (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID;(2S,3S)-TRANS-3-(CARBOXYMETHYL)AZETIDINE-2-CARBOXYLIC ACID;T-CAA;(+)-TRANS-2-CARBOXYAZETIDINE-3-ACETIC ACID;3-Azetidineaceticacid,2-carboxy-,(2S-trans)-(9CI);(2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID 98%;(2S,3S)-trans-3-(Carboxymethyl)-azetidine-2-acetic acid,98%;(2S-trans)-2-Carboxy-3-azetidineacetic Acid
• CAS NO: 185387-36-4
• Molecular Formula: C7H11NO4
• Molecular Weight: 173.17
• Product Categories: CARBOXYLICACID;Heterocyclic Compounds;Neurochemicals
• Mol File: 185387-36-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 284.61°C (rough estimate)
• Flash Point: 213 °C
• Appearance: /
• Density: 1.4093 (rough estimate)
• Vapor Pressure: 1.51E-08mmHg at 25°C
• Refractive Index: 1.4860 (estimate)
• Storage Temp.: 0-6°C
• CAS DataBase Reference: (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID(185387-36-4)
• EPA Substance Registry System: (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID(185387-36-4)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 185387-36-4(Hazardous Substances Data)

Usage

Description

(2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID is a white to off-white crystalline compound with potent agonistic activity at the KA receptor (0.7uM) and strong inhibitory effects on sodium-dependent glucose uptake (5uM). It is a synthetic molecule with potential applications in various fields due to its unique chemical properties and biological activities.

Uses

Used in Pharmaceutical Industry:
(2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID is used as a potent KA receptor agonist for its ability to modulate the activity of the kainic acid receptor, which is involved in various neurological processes. This makes it a promising candidate for the development of drugs targeting neurological disorders.
(2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID is also used as a potent inhibitor of sodium-dependent glucose uptake, which can be beneficial in the development of treatments for conditions related to glucose metabolism, such as diabetes.
Used in Research and Development:
In the field of research and development, (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID serves as an important tool compound for studying the function and role of the kainic acid receptor and sodium-dependent glucose transport systems. Its use in experimental settings can help researchers gain a deeper understanding of these biological processes and contribute to the development of new therapeutic strategies.
Used in Drug Design and Optimization:
The unique properties of (2S,3S)-TRANS-3-(CARBOXYMETHYL)-AZETIDINE-2-ACETIC ACID make it a valuable starting point for the design and optimization of new drugs targeting the kainic acid receptor and glucose transport systems. Its potent activities can be leveraged to develop more effective and selective compounds with improved pharmacokinetic and pharmacodynamic profiles.

InChI:InChI=1/C6H9NO4/c8-4(9)1-3-2-7-5(3)6(10)11/h3,5,7H,1-2H2,(H,8,9)(H,10,11)/p-1/t3-,5-/m0/s1