185420-81-9

Basic information

• Product Name: (2R,3aR,6aR)-2-Dimethylcarbamoyl-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid benzyl ester
• CAS NO: 185420-81-9
• Molecular Weight: 316.4
• Mol File: 185420-81-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3aR,6aR)-2-Dimethylcarbamoyl-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3aR,6aR)-2-Dimethylcarbamoyl-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid benzyl ester(185420-81-9)
• EPA Substance Registry System: (2R,3aR,6aR)-2-Dimethylcarbamoyl-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid benzyl ester(185420-81-9)

Safety Data

• Hazardous Substances Data: 185420-81-9(Hazardous Substances Data)

Upstream product

• 138877-09-5 (1R,3R,5R)-benzyl 2-azabicyclo<3.3.0>octane-3-carboxylate hydrochloride 
• 135214-81-2 (1R,3R,5R)-2-azabicyclo<3.3.0>octane-3-carboxylic acid hydrochloride 

Downstream Products

• 185420-82-0 (2R,3aR,6aR)-Octahydro-cyclopenta[b]pyrrole-2-carboxylic acid dimethylamide 

Relevant articles and documents

Chemical differentiation of enantiotopic groups: Diastereoselective opening of a prochiral dilactone

Prochiral dilactone 1 has been synthesized and subjected to diastereoselective nucleophilic opening. The structural features of chiral, enantiomerically pure nucleophiles have been optimized regarding their capability to perform prochiral recognition at dilactone 1. 3-Ketoglutaric mono acid products 2 of dilactone opening, which are versatile building blocks for natural product synthesis, have been obtained in diastereomeric ratios up to 84:16 and were enriched by subsequent crystallization to 97.5:2.5.