185459-60-3

Basic information

• Product Name: Methanediamine, 1-(4-bromophenyl)-N,N'-bis[(4-bromophenyl)methylene]-
• CAS NO: 185459-60-3
• Molecular Formula: C21H15Br3N2
• Molecular Weight: 535.076
• Mol File: 185459-60-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanediamine, 1-(4-bromophenyl)-N,N'-bis[(4-bromophenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanediamine, 1-(4-bromophenyl)-N,N'-bis[(4-bromophenyl)methylene]-(185459-60-3)
• EPA Substance Registry System: Methanediamine, 1-(4-bromophenyl)-N,N'-bis[(4-bromophenyl)methylene]-(185459-60-3)

Safety Data

• Hazardous Substances Data: 185459-60-3(Hazardous Substances Data)

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 1029087-85-1 1,3-bis(4-bromophenyl)-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazine 
• 845747-30-0 C₂₄H₁₇Br₂NO 
• 24898-17-7 4,4'-dibromodibenzylamine 
• 36741-16-9 2,4,5-tris(4-bromophenyl)imidazole 
• 148320-68-7 2,5-di(4-bromophenyl)-3,3,4,4-tetracyanopyrrolidine 

Relevant articles and documents

Regioselective synthesis of cis- and trans-2,4,5-triarylimidazolines and 2,4,5-triarylimidazoles from available reagents

Novel data were obtained concerning the reaction of aromatic aldehydes with ammonia. A preparative method for the synthesis of new substituted 1,3,5-triaryl-2,4-diazapenta-1,4-dienes was developed. These products are the starting reactants for syntheses of cis- and trans-2,4,5-triaryl-2-imidazolines and 2,4,5-triarylimidazoles.

2,4,5-Tris(alkoxyaryl)imidazoline derivatives as potent scaffold for novel p53-MDM2 interaction inhibitors: Design, synthesis, and biological evaluation

Imidazoline-based small molecule inhibitors of p53-MDM2 interaction intended for the treatment of p53 wild-type tumors are the promising structures for design of anticancer drugs. Based on fragment approach we have investigated a key role of substituents