185527-11-1

Basic information

• Product Name: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE
• Synonyms: TERT-BUTYL 3-AMINO-2,3-DIHYDROSPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE;3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE;TERT-BUTYL 3-AMINO-2,3-DIHYDRO-1'H-SPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE;Spiro[1H-indene-1,4'-piperidine]-1'-carboxylic acid,3-aMine- 2,3-dihydro- 1,1-diMethyl ethyl ester;Tert-Butyl 3-Amino-2,3-Dihydrospiro[Indene-1,4-Piperidine]-1-Carboxylate(WX105027)
• CAS NO: 185527-11-1
• Molecular Formula: C₁₈H₂₆N₂O₂
• Molecular Weight: 302.41124
• Mol File: 185527-11-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 431.3 °C at 760 mmHg
• Flash Point: 214.6 °C
• Appearance: /
• Density: 1.14
• Storage Temp.: 2-8°C
• PKA: 9.10±0.20(Predicted)
• CAS DataBase Reference: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE(185527-11-1)
• EPA Substance Registry System: 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE(185527-11-1)

Safety Data

• Hazardous Substances Data: 185527-11-1(Hazardous Substances Data)

Usage

General Description

3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE is a chemical compound that belongs to the spirocyclic piperidine class. It is a derivative of piperidine with a spiro-indane moiety and a BOC (tert-butyloxycarbonyl) protective group attached to the nitrogen atom. 3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE is commonly used as a building block in the synthesis of various pharmaceutical drugs and biologically active molecules. Its spirocyclic structure and amino group make it a versatile intermediate for the preparation of a wide range of potential drug candidates. The protective group allows for selective functionalization of the piperidine nitrogen atom, making it a valuable tool in organic synthesis.

Downstream Products

• 937253-91-3 tert-butyl 3-(benzoylamino)-2,3-dihydro-1'H-spiro[indene-1,4'-piperidine]-1'-carboxylate 

Relevant articles and documents

AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE

A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R 5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.