185559-64-2Relevant articles and documents
Syntheses and antifilarial profile of 5-amino and 5,8-diamino-isoquinoline derivatives: A new class of antifilarial agents
Srivastava, Sanjay K.,Chauhan,Agarwal,Bhaduri,Singh,Fatma, Nigar,Chatterjee,Bose, Chhanda,Srivastava
, p. 2623 - 2628 (1996)
The syntheses of 5-amino (4-12,15) and 5,8-diamino (16-17) isoquinoline derivatives, their antifilarial activity and their effect on metabolic activities of filariids are delineated. Some of the screened compounds have shown promising filaricidal response against Acanthocheilonema viteae in rodents.