185611-88-5

Basic information

• Product Name: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-2-phenylacetylamino-propionylamino)-propionylamino]-propionic acid tert-butyl ester
• CAS NO: 185611-88-5
• Molecular Weight: 581.603
• Mol File: 185611-88-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-2-phenylacetylamino-propionylamino)-propionylamino]-propionic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-2-phenylacetylamino-propionylamino)-propionylamino]-propionic acid tert-butyl ester(185611-88-5)
• EPA Substance Registry System: (S)-3-(Bis-allyloxy-phosphoryloxy)-2-[(S)-2-((S)-2-phenylacetylamino-propionylamino)-propionylamino]-propionic acid tert-butyl ester(185611-88-5)

Safety Data

• Hazardous Substances Data: 185611-88-5(Hazardous Substances Data)

Upstream product

• 126429-21-8 diallyl diisopropylphosphoramidite 

Relevant articles and documents

Selective enzymatic removal of protecting groups from phosphopeptides: Chemoenzymatic synthesis of a characteristic phosphopeptide fragment of the raf-1 kinase

Base-labile biologically relevant phosphopeptides can advantageously be synthesized under very mild conditions and without undesired side reactions by employing the heptyl (Hep) ester as C-terminal or the phenylacetamide (PhAc) as N-terminal enzyme-labile protecting group. The lipase-mediated saponification of the heptyl ester blocking function was successfully applied in the construction of a characteristic selectively phosphorylated hydroxyamino acid fragment of Raf-1 kinase, an important member of the so-called Ras signal transduction pathway.