185674-70-8

Basic information

• Product Name: 3-Heptanone, 2-diazo-5-phenyl-
• CAS NO: 185674-70-8
• Molecular Formula: C13H16N2O
• Molecular Weight: 216.283
• Mol File: 185674-70-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Heptanone, 2-diazo-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Heptanone, 2-diazo-5-phenyl-(185674-70-8)
• EPA Substance Registry System: 3-Heptanone, 2-diazo-5-phenyl-(185674-70-8)

Safety Data

• Hazardous Substances Data: 185674-70-8(Hazardous Substances Data)

Upstream product

• 2114-36-5 1-bromopropylbenzene 
• 100-52-7 benzaldehyde 
• 100118-00-1 (1-phenyl-propyl)-malonic acid 
• 37556-02-8 diethyl 2-(1-phenylpropyl)malonate 
• 93-54-9 1-Phenyl-1-propanol 
• 1117-96-0 Diazoethan 
• 91427-14-4 3-phenylpentanoyl chloride 

Relevant articles and documents

Stereocontrol in the intramolecular Buchner reaction of diazoketones

Rhodium(II) acetate catalysed intramolecular Buchner cyclisation of a series of diazoketones 1 proceeds with excellent diastereoselectivity to produce the trans substituted azulenones 2, which exist as a rapidly equilibrating cycloheptatriene-norcaradiene system, from which the norcaradiene tautomers can be efficiently trapped as PTAD cycloadducts 4. The cyclisation-cycloaddition sequence can be conducted in either a stepwise or a tandem process, leading to the pentacyclic systems 4 as a single diastereomer in each case. In the reaction of diazoketone If intramolecular cyclopropanation competes with cyclisation to the aromatic ring.