185737-95-5

Basic information

• Product Name: 1H-Indole-3-acetic acid, 1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-, ethyl ester
• CAS NO: 185737-95-5
• Molecular Formula: C21H22BrNO3
• Molecular Weight: 416.315
• Mol File: 185737-95-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indole-3-acetic acid, 1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-acetic acid, 1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-, ethyl ester(185737-95-5)
• EPA Substance Registry System: 1H-Indole-3-acetic acid, 1-[(4-bromophenyl)methyl]-5-methoxy-2-methyl-, ethyl ester(185737-95-5)

Safety Data

• Hazardous Substances Data: 185737-95-5(Hazardous Substances Data)

Upstream product

• 3471-32-7 4-Methoxyphenylhydrazine 
• 539-88-8 4-oxopentanoic acid ethyl ester 
• 17536-38-8 ethyl 2-(5-methoxy-2-methyl-1H-indol-3-yl)acetate 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 176045-80-0 N-(4-bromobenzyl)-N-(4-methoxyphenyl)-hydrazine 

Downstream Products

• 176045-84-4 (R)-3-{(S)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-3-methyl-butyryl}-4-isopropyl-oxazolidin-2-one 
• 176200-42-3 (R)-3-{(R)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-3-methyl-butyryl}-4-isopropyl-oxazolidin-2-one 
• 176045-83-3 L-761,000 
• 176045-82-2 (E)-4-[1-(4-Bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-but-2-enoic acid ethyl ester 
• 185737-64-8 ethyl 4-(1-(4-bromobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)-3-methylbutanoate 
• 212965-13-4 2-[1-(4-bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-thioacetimidic acid 
• 212965-12-3 1-(4-bromobenzyl)-5-methoxy-2-methylindole-3-acetamide 
• 176174-97-3 p-Bromobenzyl-indomethacin 
• 176045-81-1 (1-(4-Bromobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)-acetaldehyde 

Relevant articles and documents

Thiazole analogues of the NSAID indomethacin as selective COX-2 inhibitors

The carboxyl group of the NSAID indomethacin was replaced with a variety of substituted thiazoles to obtain a series of potent, selective inhibitors of COX-2. Additional substitutions were made at the 1-position and 5-position of the indole of indomethacin.

Synthesis and biological evaluation of both enantiomers of L-761,000 as inhibitors of cyclooxygenase 1 and 2

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