1859-75-2

Basic information

• Product Name: Ethanone, 1-[2-(methylamino)phenyl]- (9CI)
• Synonyms: Ethanone, 1-[2-(methylamino)phenyl]- (9CI);1-(2-MethylaMino-phenyl)-ethanone
• CAS NO: 1859-75-2
• Molecular Formula: C₉H₁₁NO
• Molecular Weight: 149.18974
• Product Categories: ACETYLGROUP
• Mol File: 1859-75-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 33-33.5 °C
• Boiling Point: 117-118 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.062±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 2.88±0.10(Predicted)
• CAS DataBase Reference: Ethanone, 1-[2-(methylamino)phenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-(methylamino)phenyl]- (9CI)(1859-75-2)
• EPA Substance Registry System: Ethanone, 1-[2-(methylamino)phenyl]- (9CI)(1859-75-2)

Safety Data

• Hazardous Substances Data: 1859-75-2(Hazardous Substances Data)

Upstream product

• 2006-47-5 2--acetophenon 
• 24438-17-3 1,3-dimethylindolin-2-one 
• 551-93-9 2-aminoacetophenone 
• 74-88-4 methyl iodide 
• 75-05-8 acetonitrile 
• 77-78-1 dimethyl sulfate 
• 917-54-4 methyllithium 
• 1859-70-7 N-(2-acetylphenyl)-4-methylbenzenesulfonamide 
• 57056-93-6 N-methyl-2-iodoaniline 
• 1266329-42-3 N-methyl-2-[(trimethylsilyl)ethynyl]aniline 
• 923270-57-9 2-methylaminophenylacetylene 
• 1352449-03-6 1-(2-((2-iodobenzyl) (methyl)amino)phenyl)-ethan-1-one 
• 17583-40-3 2-methylaminobenzonitrile 
• 75-16-1 methylmagnesium bromide 

Downstream Products

• 128113-82-6 (1S,1'S)-N-(1'-phenylethyl)-1-<2''-(methylamino)phenyl>ethylamine 
• 128113-82-6 (1R,1'S)-N-(1'-phenylethyl)-1-<2''-(methylamino)phenyl>ethylamine 
• 125681-81-4 α-methyl-2-(methylamino)benzenemethanol 
• 40166-68-5 1-(5-bromo-2-(methylamino)phenyl)ethanone 
• 174840-91-6 2'-methylaminochalcone 
• 528856-10-2 N-(2-acetylphenyl)-2,2,2-trichloro-N-methylacetamide 
• 174840-94-9 3-hydroxy-1-methyl-2-phenyl-1,4-dihydro-4-quinolone 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 1821-38-1 N-methyl-2-ethylphenylamine 
• 128113-85-9 (1S,1'S)-N-(1'-phenylethyl)-1-(2''-chlorophenyl)ethylamine 
• 128113-78-0 <(S)-1-(2,5-dimethoxyphenyl)ethyl><(S)-1-phenylethyl>amine 
• 128113-80-4 (1S,1'S)-N-(1'-phenylethyl)-1-(2''-hydroxy-6''-methoxyphenyl)ethylamine 
• 128113-80-4 (1R,1'S)-N-(1'-phenylethyl)-1-(2''-hydroxy-6''-methoxyphenyl)ethylamine 
• 128113-91-7 (1S,1'S)-N-(1'-phenylethyl)-1-(3'',5''-dimethoxyphenyl)ethylamine 

Relevant articles and documents

Nickel/Photo-Cocatalyzed Asymmetric Acyl-Carbamoylation of Alkenes

An unprecedented asymmetric acyl-carbamoylation of pendant alkenes tethered on aryl carbamic chlorides with both aliphatic and aromatic aldehydes has been developed via the cooperative catalysis of a chiral nickel-PHOX complex and tetrabutylammonium decatungstate. This reaction represents the first example of merging hydrogen-atom-transfer photochemistry and asymmetric transition metal catalysis in difunctionalization of alkenes. Using this protocol, a variety of oxindoles bearing a challenging quaternary stereogenic center are furnished under mild conditions in highly enantioselective manner.

C–C bond-forming reactions of ground-state aryl halides under reductive activation

Under basic conditions aryl halides can undergo SRN1 reactions, BHAS reactions and benzyne formations. Appropriate complex substrates afford an opportunity to study inherent selectivities. SRN1 reactions are usually favoured under ph

Silica gel-mediated hydroamination/semipinacol rearrangement of 2-alkylaminophenylprop-1-yn-3-ols: Synthesis of 2-oxindoles from alkynes and 1-(2-aminophenyl) ketones

2-Alkylaminophenylprop-1-yn-3-ols, prepared from the lithium diisopropylamide (LDA)- mediated 1,2-addition of alkynes to 1-(2-aminophenyl) ketones, can be converted to 3,3-disubstituted 2-oxindoles by using silica gel in n-hexane/ ethyl acetate (20:1 v/v) as the reaction medium. The utility of the approach as a potential scale-up strategy for the synthesis of 2-oxindoles was exemplified by the large-scale synthesis of one adduct in excellent yield. The synthetic applicability of this chemistry was also demonstrated by the recycling of the silica gel up to 8 times with no apparent loss of activity being observed for the same example.