18614-66-9

Basic information

• Product Name: 4-Hydroxy-2-methyl-3-nitropyridine
• Synonyms: 4-Hydroxy-2-methyl-3-nitropyridine;2-Methyl-3-nitropyridin-4-ol;2-methyl-3-nitro-4-pyridinol;2-methyl-3-nitropyridin-4-ol(WX191410)
• CAS NO: 18614-66-9
• Molecular Formula: C₆H₆N₂O₃
• Molecular Weight: 154.12344
• Mol File: 18614-66-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 273 °C(Solv: water (7732-18-5))
• Boiling Point: 354.1±37.0 °C(Predicted)
• Appearance: /
• Density: 1.411±0.06 g/cm3(Predicted)
• PKA: -0.04±0.20(Predicted)
• CAS DataBase Reference: 4-Hydroxy-2-methyl-3-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy-2-methyl-3-nitropyridine(18614-66-9)
• EPA Substance Registry System: 4-Hydroxy-2-methyl-3-nitropyridine(18614-66-9)

Safety Data

• Hazardous Substances Data: 18614-66-9(Hazardous Substances Data)

Usage

Description

4-Hydroxy-2-methyl-3-nitropyridine is a chemical compound with the molecular formula C6H6N2O3. It is a yellow crystalline solid with a molecular weight of 154.12 g/mol. This nitro derivative of pyridine contains a hydroxy and a methyl group, making it useful in various chemical reactions and processes. Its properties and reactivity make it a valuable intermediate in organic synthesis and industrial applications.

Uses

Used in Pharmaceutical Synthesis:
4-Hydroxy-2-methyl-3-nitropyridine is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into complex organic molecules, contributing to the development of new drugs.
Used in Agrochemical Production:
In the agrochemical industry, 4-Hydroxy-2-methyl-3-nitropyridine is used as a building block in the creation of various agrochemicals, aiding in the development of pesticides and other agricultural products.
Used in Dye and Pigment Manufacturing:
4-Hydroxy-2-methyl-3-nitropyridine is utilized in the production of dyes and pigments due to its chemical structure that can impart color and stability to these products, making it suitable for a range of applications in the dye and pigment industry.

Upstream product

• 18614-65-8 2-methyl-4-pyridinol nitrate 
• 18437-58-6 3-methyl-4-pyridinamine 
• 5470-66-6 2-methyl-4-nitropyridine N-oxide 
• 18615-86-6 2-Methyl-4-hydroxypyridine 
• 6890-60-4 4-methoxy-2-methylpyridine 1-oxide 
• 24103-75-1 4-methoxy-2-methylpyridine 
• 931-19-1 2-methylpyridine N-oxide 

Downstream Products

• 23056-35-1 4-chloro-2-methyl-3-nitropyridine 
• 121845-73-6 5-methylpyrido[3,4-e]-1,2,4-triazine 
• 121845-74-7 3,5-dimethylpyrido[3,4-e]-1,2,4-triazine 
• 121845-75-8 5-methyl-3-(4-pyridinyl)pyrido[3,4-e]-1,2,4-triazine 
• 23056-49-7 4-bromo-2-methyl-3-nitropyridine 
• 1256806-33-3 7-bromo-1H-pyrazolo[4,3-b]pyridine 

Relevant articles and documents

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

PYRAZOLO[4,3-B]PYRIDINE-7-AMINE INHIBITORS OF ALK5

The present invention provides ALK5 inhibitors of the formula (I) wherein the variables are as defined herein. Also provided are pharmaceutical compositions, methods of making the compounds and intermediates thereof; and methods of using the compounds.

Nitration of 2-methyl-4-hydroxypyridine and 2-methyl-4-ethoxypyridine

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