186144-56-9Relevant articles and documents
Enantioselective analysis of an asymmetric reaction using a chiral fluorosensor
Tumambac, Gilbert E.,Wolf, Christian
, p. 4045 - 4048 (2005)
(Chemical Equation Presented) An axially chiral 1,8-dipyridylnaphthalene N,N′-dioxide has been employed in enantioselective fluorescence analysis of the enzymatic kinetic resolution of trans-1,2-diaminocyclohexane. The procedure eliminates cumbersome purification and derivatization steps required by traditional methods. The results demonstrate the potential of fluorescence spectroscopy using suitable chiral chemosensors for real-time analysis of the enantiomeric composition of chiral compounds and for high-throughput screening of asymmetric reactions.