18618-55-8 Usage
Description
Cerium(III) chloride heptahydrate is a colorless crystalline solid that acts as a mild Lewis acid. It is known for its participation in various organic synthesis reactions, such as the allylation of aldehydes and Michael-type additions. It is also used as a reducing agent in place of sodium borohydride and as an efficient catalyst in certain reactions.
Uses
Used in Organic Synthesis:
Cerium(III) chloride heptahydrate is used as a reducing agent for the conversion of esters to allylsilanes in organic synthesis. It serves as an alternative to sodium borohydride, providing a milder and more selective reduction process.
Used in the Luche Reduction:
In the Luche reduction, cerium(III) chloride heptahydrate is used to selectively produce allylic alcohols from ketones, such as carvone, making it a valuable tool in the synthesis of complex organic molecules.
Used in the Synthesis of 2-Quinolones:
Cerium(III) chloride heptahydrate acts as a catalyst in the solvent-free microwave-assisted synthesis of 2-quinolones via the condensation of α-ketoesters with o-anilinoketones. This application demonstrates its versatility in promoting various organic reactions.
Used in the Beckmann Rearrangement:
When coupled with NaI, cerium(III) chloride heptahydrate promotes the Beckmann rearrangement of oximes, further showcasing its utility in organic chemistry.
Used in Michael-Type Addition:
Cerium(III) chloride heptahydrate, in combination with sodium iodide supported on silica gel, efficiently promotes the Michael addition of 1,3-dicarbonyl compounds to α,β-unsaturated ketones and α,β-unsaturated aldehydes. This application highlights its role as an effective catalyst in enhancing the reactivity of certain organic reactions.
Check Digit Verification of cas no
The CAS Registry Mumber 18618-55-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,6,1 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18618-55:
(7*1)+(6*8)+(5*6)+(4*1)+(3*8)+(2*5)+(1*5)=128
128 % 10 = 8
So 18618-55-8 is a valid CAS Registry Number.
InChI:InChI=1/Ce.3ClH.7H2O/h;3*1H;7*1H2/q+3;;;;;;;;;;/p-3