18651-16-6 Usage
Description
2-Methyoxy-3-methyl-2-phenyl-4H-benzo-g-pyranone is a chemical compound that belongs to the class of flavonoids. It is characterized by the presence of a benzopyranone core structure, with a methyl group at the 3-position, a methoxy group at the 2-position, and a phenyl group at the 2-position. 2-Methyoxy-3-methyl-2-phenyl-4H-benzo-g-pyranone exhibits unique chemical and biological properties, making it a valuable intermediate in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
2-Methyoxy-3-methyl-2-phenyl-4H-benzo-g-pyranone is used as an intermediate in the synthesis of Dimefline Hydrochloride (D448250), a new respiratory stimulant drug. Its unique structure and properties contribute to the development of this drug, which has potential applications in treating respiratory disorders and improving lung function.
As an intermediate in the synthesis of pharmaceutical compounds, 2-Methyoxy-3-methyl-2-phenyl-4H-benzo-g-pyranone plays a crucial role in the development of new drugs with potential therapeutic benefits. Its presence in the molecular structure of Dimefline Hydrochloride highlights its importance in the pharmaceutical industry, where it can be further explored for its potential applications in the treatment of various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 18651-16-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,6,5 and 1 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 18651-16:
(7*1)+(6*8)+(5*6)+(4*5)+(3*1)+(2*1)+(1*6)=116
116 % 10 = 6
So 18651-16-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H14O3/c1-11-16(18)14-9-8-13(19-2)10-15(14)20-17(11)12-6-4-3-5-7-12/h3-10H,1-2H3
18651-16-6Relevant articles and documents
Preparation method and application of dimenephrine hydrochloride intermediate 7-methoxy-3-methyl flavone
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Paragraph 0017-0022, (2021/04/10)
The invention provides a preparation method of a dimenephrine hydrochloride intermediate 7-methoxy 3-methyl flavone, which comprises the following steps: carrying out cyclization reaction on a compound IIa: 2, 4-dihydroxy propiophenone and a compound IIb: benzoyl chloride under the action of sodium benzoate to obtain a compound III: 7-methoxy-3-methyl flavone; according to the preparation method of the intermediate 7-methoxy-3-methyl flavone, provided by the invention, methylated 2, 4-dihydroxy propiophenone and benzoyl chloride are synthesized by adopting a one-step method, so that the prepared intermediate 7-methoxy-3-methyl flavone is high in purity, few in process impurities, high in yield and simple to operate; the invention further provides application of the 7-methoxy 3-methyl flavone in preparation of the dimenephrine hydrochloride, the yield of the dimenephrine hydrochloride is higher, and the specific preparation operation process is simple.
Antioxidant and antibacterial activity of new 3-methylflavones
Jayashree,Alam, Afroze,Kumar, D. Vijay,Nayak, Yogendra
experimental part, p. 237 - 240 (2011/12/15)
Synthesis of new 3-methylflavones with various substitution on the ring A and B is being described. They were evaluated for antioxidant and antibacterial activity against Gram positive and Gram negative bacteria. Test compounds such as F-4,9,11,12 and 20
