186521-98-2 Usage
Description
(3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE is a chemical compound that features a BOC-protected amine and a diazo group. It is utilized in organic synthesis for the incorporation of an amino group into organic molecules. The BOC-protected amine can be deprotected under mild conditions, revealing the free amine, which is beneficial for the alteration of biomolecules and the creation of pharmaceuticals. Additionally, the diazo group allows for a range of transformations, such as cyclopropanation and aziridination, rendering (3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE a significant intermediate in organic chemistry. However, due to the inherent risks associated with diazo compounds, it is imperative to exercise proper safety measures when handling this chemical.
Uses
Used in Organic Synthesis:
(3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE is used as a reagent for the introduction of an amino group into organic molecules, which is crucial for the synthesis of various organic compounds.
Used in Biomolecule Modification:
(3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE is used as a modifying agent for biomolecules, enabling the attachment of an amino group to these molecules, which can be particularly useful in the development of new pharmaceuticals.
Used in Pharmaceutical Synthesis:
(3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE is used as an intermediate in the synthesis of pharmaceuticals, where the BOC-protected amine can be deprotected to facilitate the formation of the desired drug molecules.
Used in Chemical Transformations:
(3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE is used as a versatile intermediate for various chemical transformations, such as cyclopropanation and aziridination, which are important reactions in the field of organic chemistry.
Used in Research and Development:
(3S)-3-BOC-AMINO-1-DIAZO-2-BUTANONE is used in research and development for exploring new synthetic pathways and developing innovative applications in the chemical and pharmaceutical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 186521-98-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,5,2 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 186521-98:
(8*1)+(7*8)+(6*6)+(5*5)+(4*2)+(3*1)+(2*9)+(1*8)=162
162 % 10 = 2
So 186521-98-2 is a valid CAS Registry Number.
186521-98-2Relevant articles and documents
Total synthesis of (-)-epimyrtine by a gold-catalyzed hydroamination approach
Trinh, Thi Thanh Huyen,Nguyen, Khanh Hung,De Aguiar Amaral, Patricia,Gouault, Nicolas
, p. 2042 - 2047 (2013)
A new approach to the total synthesis of (-)-epimyrtine has been developed from D-alanine. The key step to access the enantiopure pyridone intermediate was achieved by a gold-mediated cyclization. Finally, various transformations afforded the natural prod
Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicines
-
Paragraph 0317; 0319; 0322; 0323, (2018/09/08)
The present invention relates to an amine compound for inhibiting SSAO/VAP-1 and application thereof in medicines. In particular, the present invention relates to an amine compound for inhibiting a semicarbazide-sensitive oxidase (SSAO) and/or vascular adhesion protein-1 (VAP-1) inhibitor, or a pharmaceutically acceptable salt thereof, a stereoisomer or an/a E/Z isomer, further relates to a pharmaceutical composition containing the amine compound. The invention further relates to the application of the amine compound and the pharmaceutical composition in manufacture of the medicines for treatment of inflammation, inflammation-related diseases and immune diseases.
TAPP analogs containing β3-homo-amino acids: Synthesis and receptor binding
Podwysocka,Kosson,Lipkowski,Olma, Aleksandra
, p. 556 - 559 (2012/11/07)
β-Amino acids containing α,β-hybrid peptides show great potential as peptidomimetics. In this paper, we describe the synthesis and affinity to μ-opioid and δ-opioid receptors of α,β-hybrids, analogs of the tetrapeptide Tyr- d-Ala-Phe-Phe-NH2 (TAPP). Each amino acid was replaced with an l- or d-β3-h-amino acid. All α,β-hybrids of TAPP analogs were synthesized in solution and tested for affinity to μ-opioid and δ-opioid receptors. The analog Tyr-β3h- d-Ala-Phe-PheNH2 was found to be as active as the native tetrapeptide.
