186589-12-8

Basic information

• Product Name: 4-BROMO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
• Synonyms: 4-BROMO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE;4-Bromo-1-isocyanato-2-(trifluoromethyl)benzene
• CAS NO: 186589-12-8
• Molecular Formula: C8H3BrF3NO
• Molecular Weight: 266.01
• Product Categories: Isocyanates;Nitrogen Compounds;Organic Building Blocks;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 186589-12-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 115 °C10 mm Hg(lit.)
• Flash Point: 230 °F
• Appearance: /
• Density: 1.699 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0497mmHg at 25°C
• Refractive Index: n20/D 1.524(lit.)
• CAS DataBase Reference: 4-BROMO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE(186589-12-8)
• EPA Substance Registry System: 4-BROMO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE(186589-12-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• RIDADR: UN 2206 6.1/PG 3
• WGK Germany: 3
• HazardClass: KEEP COLD, LACHRYMATOR, TOXIC, C
• Hazardous Substances Data: 186589-12-8(Hazardous Substances Data)

Usage

General Description

4-Bromo-2-(trifluoromethyl)phenyl isocyanate is a chemical compound with the molecular formula C8H4BrF3NO. It is a highly reactive and toxic compound that is commonly used in the production of pharmaceuticals, agrochemicals, and polymers. It is also used in the synthesis of various organic compounds. This chemical has potential health hazards and should be handled with care, as it can cause skin and eye irritation, respiratory issues, and other adverse effects if not properly handled. Additionally, it is important to avoid inhalation or ingestion of this compound, as it can be harmful to human health with extended exposure.

InChI:InChI=1/C8H3BrF3NO/c9-5-1-2-7(13-4-14)6(3-5)8(10,11)12/h1-3H

Relevant articles and documents

Imidazolidine Derivatives, Uses Therefor, Preparation Thereof and Compositions Comprising Such

Compounds of formula (I): wherein X is O or S, R1 is acyl, aldehyde, cycloalkyl, an optionally substituted alkyl, alkenyl or alkynyl, R2 is H. alkyl, hydroxyalkyl, haloalkyl, alkenyl, or alkynyl; substituted alkyl; alkylcarbonyl; R3 and R4 are H, halogen, alkyl, alkenyl, alkynyl, alkoxyl, alkylthio, hydroxyalkyl, haloalkyl, haloalkenyl, or haloalkynyl; or R3 and R4 form an, optionally aromatic or heterocyclic, optionally substituted ring, R5 is H, halogen, trifluoromethyl, —CN, or —NO2; not all of R3, R4, and R5 being H, R6 and R9 are H, halogen, OH; alkyl. hydroxyalkyl, alkoxyl, thioalkyl, haloalkyl, alkenyl, or alkynyl; R7 and R8 are H, halogen, OH, SH; alkoxyl or alkylthio optionally substituted by OH and/or halogen; one of R7 and R8 not being H or halogen; or one of R7 and R8 is a pharmaceutically acceptable ester or thioester grouping, or R6 is C1-3-alkyl or, together with either R1 or R2, represents C1-3 alkylene or alkenylene linking group, optionally substituted by methyl, trifluoromethyl, OH, or halogen, and pharmaceutically acceptable salts and esters thereof, are useful as selective androgen modulators.