18676-07-8 Usage
General Description
Hispanolone is a chemical compound primarily found in the bark of the Pygeum africanum tree. It is a natural steroid and has been shown to have anti-inflammatory, anti-androgenic, and anti-estrogenic properties. Hispanolone is commonly used in traditional medicine to treat symptoms of benign prostatic hyperplasia (BPH) and related conditions. Its anti-inflammatory effects may help reduce swelling and discomfort in the prostate, while its anti-androgenic properties may help to inhibit the production of hormones that contribute to BPH. Additionally, its anti-estrogenic properties may help to balance hormone levels in the body. Hispanolone has also been researched for potential applications in addressing acne, baldness, and other hormonal disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 18676-07-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,6,7 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18676-07:
(7*1)+(6*8)+(5*6)+(4*7)+(3*6)+(2*0)+(1*7)=138
138 % 10 = 8
So 18676-07-8 is a valid CAS Registry Number.
InChI:InChI=1/C20H30O3/c1-14-16(21)12-17-18(2,3)8-5-9-19(17,4)20(14,22)10-6-15-7-11-23-13-15/h7,11,13-14,17,22H,5-6,8-10,12H2,1-4H3/t14-,17+,19+,20-/m1/s1
18676-07-8Relevant articles and documents
PREHISPANOLONE, A LABDANE DITERPENE FROM LEONURUS HETEROPHYLLUS
Hon, Po-Ming,Lee, Chi-Ming,Shang, Hong-Sheng,Cui, Yu-Xin,Wong, Henry N. C.,Chang, Hson-Mou
, p. 354 - 356 (1991)
A new labdane diterpene, prehispanolone, has been isolated from Leonurus heterophyllus.Its structure, 9α,13R;15,16-diepoxylabdan-14-en-7-one, was established by spectroscopic means as well as by examination of its derivatives.
Total syntheses of naturally occurring molecules possessing 1,7- dioxaspiro[4.4]nonane skeletons
Wong, Henry N. C.
, p. 1757 - 1765 (2007/10/03)
The syntheses of several naturally occurring molecules, namely prehispanolone, sphydrofuran, secosyrins, and syringolides are reviewed. Interestingly, these compounds are all structurally related, possessing a 1,7-dioxaspiro[4.4]nonane framework. The pivotal step in these synthetic endeavors involves the peracid oxidation of substituted 2- trimethylsilylfurans to but-2-en-4-olides. A subsequent intramolecular Michael addition procedure was also essential in the construction of the spiro skeleton. Two significant issues concerning regioselectivity and stereoselectivity are also addressed.