186792-78-9

Basic information

• Product Name: (2-methylindolin-1-yl)(phenyl)methanone
• Synonyms: (2-methylindolin-1-yl)(phenyl)methanone
• CAS NO: 186792-78-9
• Molecular Weight: 237.301
• Mol File: 186792-78-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (2-methylindolin-1-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methylindolin-1-yl)(phenyl)methanone(186792-78-9)
• EPA Substance Registry System: (2-methylindolin-1-yl)(phenyl)methanone(186792-78-9)

Safety Data

• Hazardous Substances Data: 186792-78-9(Hazardous Substances Data)

Upstream product

• 111457-18-2 N-(2-allyl-phenyl)-benzamide 
• 98-88-4 benzoyl chloride 
• 6872-06-6 2-methyl indoline 
• 100-52-7 benzaldehyde 

Downstream Products

• 55-21-0 benzamide 
• 579-93-1 2-(Benzoylamino)benzoic Acid 
• 144-62-7 oxalic acid 
• 65-85-0 benzoic acid 
• 89-52-1 o-acetylamino-benzoic acid 

Relevant articles and documents

Carbon bridged bis-amide-based rare-earth amine compound and its preparation and with [...][...] synthesis reaction in the application of the

The invention discloses a carbon-bridged diacylamino rare earth amide with a general formula of {LLn[N(SiMe3)2]}2, wherein Ln is a rare earth metal selected from lanthanum, neodymium, samarium and yttrium, L represents a carbon-bridged diacylamino ligand, and n may be 1, 2 or 3 and can represent different ligands. The chemical structural formula of the carbon-bridged diacylamino rare earth amide differs with changes of the rare earth metal and the ligand. The invention targetedly discloses four chemical structural formulas of the rare earth amide as shown in the general formula. The carbon-bridged diacylamino rare earth amide provided by the invention is simple to synthesize, has definite structure and high yield and is easy to separate and purify. The invention also provides a preparation method for the rare earth amide and a method for applying the rare earth amide as a catalyst for catalysis of amidation of aldehyde and amine. The application method has the advantages of mild conditions, high activity, good selectivity, a wide substrate adaptation scope, a small catalyst amount and high product yield.

N-tosyl-(S)-prolyl chloride in kinetic resolution of racemic heterocyclic amines

The kinetic resolution of racemic heterocyclic amines via acylation with N-tosyl-(S)-prolyl chloride was systematically investigated. It was established that racemic mixtures of aromatic amines could be resolved with high efficiency, while the acylation of 2- and 3-methylpiperidines occurred with low diastereoselectivity. A method for the preparation of enantiomerically pure (3R)-7,8-difluoro-3-methyl-3,4-dihydro-2H-[1,4]benzoxazine was developed.

Synthesis of indolines and quinoline Via cyclization of N-arylsulfonyl-2-allylanilines catalyzed by bronsted acid

N-Arylsulfonyl-2-allylanilines underwent the intramolecular hydroamination to produce indolines or quinoline in the presence of catalytic amount of triflic acid with good yield. The scope of the reaction was extended to other N-protected aminoalkenes.