186834-07-1

Basic information

• Product Name: methyl N-(2-bromopropanoyl)-3-cyano-4,5-dimethylanthranilate
• CAS NO: 186834-07-1
• Molecular Weight: 339.189
• Mol File: 186834-07-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl N-(2-bromopropanoyl)-3-cyano-4,5-dimethylanthranilate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-(2-bromopropanoyl)-3-cyano-4,5-dimethylanthranilate(186834-07-1)
• EPA Substance Registry System: methyl N-(2-bromopropanoyl)-3-cyano-4,5-dimethylanthranilate(186834-07-1)

Safety Data

• Hazardous Substances Data: 186834-07-1(Hazardous Substances Data)

Upstream product

• 73318-14-6 methyl(3-cyano-4,5-dimethylantnranilate) 
• 7148-74-5 2-Bromopropionyl chloride 

Relevant articles and documents

Synthesis, local anaesthetic and antiarrhythmic activity of methyl N-(2-substituted aminopropanoyl)-3-cyanoanthranilates

A series of methyl N-(2-substituted aminopropanoyl)-3-cyanoanthranilates (4a-i), that are structurally-related to tocainide and lidocaine, was synthesized and was found to be active when evaluated for local anaesthetic activity using the frog-foot withdrawal reflex, the guinea pig wheal derm and the rabbit corneal reflex tests. A selected numbers of the series were preliminarily evaluated for antiarrhythmic activity using CaCl2-induced arrhythmia test. Compounds 4a, 4c and 4f at lower doses completely protected the animals against the induced arrhythmias.