18691-30-0

Basic information

• Product Name: 3′-(phenyl)dispiro[indene-2,1′-cyclopropane-2′,2′′-indene]-1,1′′,3,3′′-tetraone
• Synonyms: 3′-(phenyl)dispiro[indene-2,1′-cyclopropane-2′,2′′-indene]-1,1′′,3,3′′-tetraone
• CAS NO: 18691-30-0
• Molecular Weight: 378.384
• Mol File: 18691-30-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3′-(phenyl)dispiro[indene-2,1′-cyclopropane-2′,2′′-indene]-1,1′′,3,3′′-tetraone(CAS DataBase Reference)
• NIST Chemistry Reference: 3′-(phenyl)dispiro[indene-2,1′-cyclopropane-2′,2′′-indene]-1,1′′,3,3′′-tetraone(18691-30-0)
• EPA Substance Registry System: 3′-(phenyl)dispiro[indene-2,1′-cyclopropane-2′,2′′-indene]-1,1′′,3,3′′-tetraone(18691-30-0)

Safety Data

• Hazardous Substances Data: 18691-30-0(Hazardous Substances Data)

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 100-52-7 benzaldehyde 
• 7319-63-3 2-bromo-indan-1,3-dione 
• 5381-33-9 2-benzylidene-indan-1,3-dione 

Relevant articles and documents

One-pot, fast cyclopropanation reaction of indandione with various aldehydes in the presence of cyanogen bromide and trimethylamine

A new, fast, and easy one-pot cyclopropanation reaction of aromatic and aliphatic aldehydes with 1H-indene-1,3(2H)-dione and cyanogen bromide (BrCN) was developed for synthesizing 3′-(aryl[alkyl])-dispiro[indan-2,1′-cyclopropane-2′,2′′-indan]-1,1′′,3,3′′-

Synthesis of activated cyclopropanes by an MIRC strategy: An enantioselective organocatalytic approach to spirocyclopropanes

An efficient cyclopropanation, by a Michael-initiated ring-closing (MIRC) reaction of 2-arylidene-1,3-indandiones and 2-arylidene malononitriles, has been developed by using different α-monohalogenated methylene active compounds with triethylamine. The first enantioselective cyclopropanation to spirocyclopropanes derived by the reaction of 2-arylidene-1,3-indandiones and dimethyl bromomalonate with a commercially available α,α-L- diarylprolinol as the organocatalyst and K2CO3 as the additive has been accomplished. The spirocyclopropanes were isolated in high yield and up to 85% ee. Notably, the asymmetric one-pot sequential approach to spirocyclopropanes proved to be a feasible process. A simple triethylamine-promoted domino cyclopropanation of 2-arylidene-1,3-indandiones and 2-arylidenemalononitriles with α-monohalogenated methylene-active compounds has been efficiently developed. Spirocyclopropanes derived from 2-arylidene-1,3-indandiones were synthesized with up to 85% ee by using dimethyl bromomalonate and α,α-L-diarylprolinol/K2CO3 system. Copyright