186968-54-7

Basic information

• Product Name: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-p-tolyl-methanol
• Synonyms: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-p-tolyl-methanol
• CAS NO: 186968-54-7
• Molecular Weight: 270.265
• Mol File: 186968-54-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-p-tolyl-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-p-tolyl-methanol(186968-54-7)
• EPA Substance Registry System: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-p-tolyl-methanol(186968-54-7)

Safety Data

• Hazardous Substances Data: 186968-54-7(Hazardous Substances Data)

Upstream product

• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 4090-60-2 5,5-dimethyl-1,3-dioxaphosphorinan-2-oxide 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 186968-69-4 2-(Bromo-p-tolyl-methyl)-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide 
• 186968-68-3 2-(Chloro-p-tolyl-methyl)-5,5-dimethyl-[1,3,2]dioxaphosphinane 2-oxide 

Relevant articles and documents

Design, synthesis and herbicidal activity of novel cyclic phosphonates with diaryl ethers containing pyrimidine

Thirteen novel cyclic phosphates were rationally designed and synthesized by introducing diary ethers containing pyrimidine. All the target compounds were characterized by 1H, 13C, 31P NMR and HRMS. The test of herbicidal activity indicated that most of the compounds showed good herbicidal activities against Amaranthus retroflexus. The compounds IA-2 (1-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)propyl-2-((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate) and IA-3 ((5,5-dimethyl-2-oxido-1,3,2-dioxaphosphinan-2-yl)(phenyl)methyl-2-((4,6-dimethoxypyrimidin-2-yl)oxy)benzoate) exhibited remarkable post-emergency herbicidal activity against the tested monocotyledonous weed at the dosage of 112.5 g ai/ha.

Synthesis of new α-hydroxy-, α-halogeno- and vinylphosphonates derived from 5,5-dimethyl-1,3,2-dioxaphosphinan-2-one

Several α-hydroxyphosphonates have been prepared by the Pudovik reaction of the cyclic phosphite 5,5-dimethyl-1,3,2-dioxaphosphinan-2-one with aldehydes and β-oxo aldehydes. These can be readily converted to α-chloro- or α-bromophosphonates in excellent yield by simply treating them with thionyl chloride or bromide. Reaction with phosphorus triiodide gave α-iodophosphonates and α-hydridophosphonates. The Pudovik products obtained from β-oxo aldehydes can be readily dehydrated to give vinylphosphonates.