186968-55-8

Basic information

• Product Name: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-m-tolyl-methanol
• Synonyms: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-m-tolyl-methanol
• CAS NO: 186968-55-8
• Molecular Weight: 270.265
• Mol File: 186968-55-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-m-tolyl-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-m-tolyl-methanol(186968-55-8)
• EPA Substance Registry System: (5,5-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-m-tolyl-methanol(186968-55-8)

Safety Data

• Hazardous Substances Data: 186968-55-8(Hazardous Substances Data)

Upstream product

• 4090-60-2 5,5-dimethyl-1,3-dioxaphosphorinan-2-oxide 
• 620-23-5 m-tolyl aldehyde 

Relevant articles and documents

Cobalt-Catalyzed Markovnikov-Selective Radical Hydroacylation of Unactivated Alkenes with Acylphosphonates

Acylphosphonates having the 5,5-dimethyl-1,3,2-dioxophosphinanyl skeleton are developed as efficient intermolecular radical acylation reagents, which enable the cobalt-catalyzed Markovnikov hydroacylation of unactivated alkenes at room temperature under mild conditions. The protocol exhibits broad substrate scope and wide functional group compatibility, providing branched ketones in satisfactory yields. A mechanism involving the Co-H mediated hydrogen atom transfer and subsequent trapping of alkyl radicals by acylphosphonates is proposed.