187283-49-4Relevant articles and documents
Total synthesis of epothilone A: The olefin metathesis approach
Yang,He,Vourloumis,Vallberg,Nicolau
, p. 166 - 168 (2007/10/03)
A flexible alterative route to the total synthesis of the antitumor agent epothilone A has been achieved by a highly convergent strategy involving olefin metathesis as a key step. The strategy may allow the chemical synthesis of a library of designed epothilones for biological screening.