18729-52-7

Basic information

• Product Name: 2-phenyl-1-cyclopropylethanol
• Synonyms: 2-phenyl-1-cyclopropylethanol
• CAS NO: 18729-52-7
• Molecular Weight: 162.232
• Mol File: 18729-52-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-phenyl-1-cyclopropylethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-1-cyclopropylethanol(18729-52-7)
• EPA Substance Registry System: 2-phenyl-1-cyclopropylethanol(18729-52-7)

Safety Data

• Hazardous Substances Data: 18729-52-7(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 1489-69-6 Cyclopropanecarboxaldehyde 
• 6921-34-2 benzylmagnesium chloride 
• 14113-94-1 2-phenyl-1-cyclopropylethan-1-one 

Downstream Products

• 171514-47-9 (E)-5-bromo-1-phenylpent-2-ene 

Relevant articles and documents

Application method of Grignard reaction

The invention discloses an application method of a Grignard reaction, belonging to the technical field of organic synthesis. According to the invention, a two-way dropwise adding mode is adopted, andpreparation of a Grignard reagent and a Grignard reaction are carried out at the same time; as the Grignard reaction is carried out while the Grignard reagent is prepared, the concentration of the Grignard reagent in a reaction system is reduced, and coupling side reactions are reduced; the use amount of a solvent in the reaction system is reduced, the accumulation rate of raw materials is increased, yield is increased and cost is reduced; and meanwhile, in the reaction system, the activity of the Grignard reagent in the system is reduced due to the reduction of the concentration of the Grignard reagent, so an explosion risk caused by over-high concentration of the Grignard reagent during storage and reaction of the Grignard reagent is avoided.