187344-68-9 Usage
Description
(6-Bromo-8-(methylamino)imidazo[1,2-a]pyrazin-3-yl)methanol, a chemical compound with the molecular formula C9H10BrN5O, is a white to off-white solid. It belongs to the class of imidazo[1,2-a]pyrazine derivatives and is characterized by the presence of a bromine atom, a methylamino group, and a hydroxyl group. (6-BROMO-8-(METHYLAMINO)IMIDAZO[1,2-A]PYRAZIN-3-YL)METHANOL is primarily used as a reagent or intermediate in the synthesis of various pharmaceutical compounds and is also utilized in the research and development of new drugs due to its potential pharmacological properties. Its structural features suggest that it may exhibit biological activity, making it a subject of interest in medicinal chemistry research.
Uses
Used in Pharmaceutical Synthesis:
(6-Bromo-8-(methylamino)imidazo[1,2-a]pyrazin-3-yl)methanol is used as a reagent or intermediate for the synthesis of various pharmaceutical compounds. Its unique structural features, including the bromine atom, methylamino group, and hydroxyl group, contribute to its versatility in the development of new drugs.
Used in Medicinal Chemistry Research:
(6-BROMO-8-(METHYLAMINO)IMIDAZO[1,2-A]PYRAZIN-3-YL)METHANOL is used as a subject of interest in medicinal chemistry research due to its potential pharmacological properties and structural features. The presence of a bromine atom, a methylamino group, and a hydroxyl group may contribute to its biological activity, making it a valuable candidate for further investigation and development in the field of drug discovery.
Used in Drug Development:
(6-Bromo-8-(methylamino)imidazo[1,2-a]pyrazin-3-yl)methanol is employed in the research and development of new drugs, as its structural characteristics and potential pharmacological properties make it a promising candidate for the creation of novel therapeutic agents. Its use in this application aims to advance the discovery and development of innovative medications to address various health conditions and diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 187344-68-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,3,4 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 187344-68:
(8*1)+(7*8)+(6*7)+(5*3)+(4*4)+(3*4)+(2*6)+(1*8)=169
169 % 10 = 9
So 187344-68-9 is a valid CAS Registry Number.
187344-68-9Relevant articles and documents
Synthesis and Antibronchospastic Activity of 8-Alkoxy- and 8-(Alkylamino)imidazopyrazines
Bonnet, Pierre A.,Michel, Alain,Laurent, Florence,Sablayrolles, Claire,Rechencq, Eliane,et al.
, p. 3353 - 3358 (2007/10/02)
Theophylline still occupies a dominant place in asthma therapy.Unfortunatly its adverse central nervous system (CNS) stimulant effects can dramatically limit its use, and adjustments in the dosage are often needed.We have synthesized a new series of imidazopyrazine derivatives which are much more potent bronchodilators than theophylline in vivo and do not exhibit the CNS stimulatory profile.In vitro studies on isolated rat uterus and guinea pig trachea confirm the high potentialities of these derivatives. 6-Bromo-8-(methylamino)imidazopyrazine-3-carbonitrile (23) is identified as the most potent compound of the series.As i n the case of theophylline, phosphodiesterase inhibition appears unlikely to be the unique mechanism of the action of this series of heterocycles.
