18747-42-7 Usage
Description
1-(1-Methyl-2-piperidinyl)acetone is an alkaloid compound that occurs naturally in the bark of Punica Granatum L. It is an oily liquid with an alkaline reaction and is miscible with water. 1-(1-Methyl-2-piperidinyl)acetone is optically inactive and can be resolved into its optically active components. It forms various derivatives such as hydrochloride, hydrobromide, aurichloride, and picrate, each with distinct melting points. 1-(1-Methyl-2-piperidinyl)acetone can also form semicarbazone, oxime, and hydrazone derivatives. Oxidation with chromic acid in H2SO4 yields N-methylpiperidine-2-carboxylic acid.
Uses
1-(1-Methyl-2-piperidinyl)acetone has various applications in different industries, including:
Used in Pharmaceutical Industry:
1-(1-Methyl-2-piperidinyl)acetone is used as an active pharmaceutical ingredient for the development of drugs targeting various medical conditions. Its unique chemical structure and properties make it a promising candidate for drug discovery and development.
Used in Chemical Synthesis:
1-(1-Methyl-2-piperidinyl)acetone serves as a key intermediate in the synthesis of various organic compounds and pharmaceuticals. Its versatile chemical properties allow for the formation of different derivatives, making it a valuable building block in organic chemistry.
Used in Research and Development:
1-(1-Methyl-2-piperidinyl)acetone is utilized in research laboratories for studying its chemical properties, reactivity, and potential applications in various fields. Its unique structure and properties make it an interesting subject for scientific investigation and exploration.
Used in Analytical Chemistry:
1-(1-Methyl-2-piperidinyl)acetone can be employed as a reference compound or standard in analytical chemistry for the development and validation of analytical methods, such as chromatography, spectroscopy, and other techniques. Its distinct properties make it suitable for use as a benchmark in these applications.
References
Piccinini., Gazzetta, 29, ii, 311 (1899)
Hess et al., Ber., SO, 344, 1386 (1917)
Hess et al., ibid, 51,741 (1918)
Hess et al., ibid, 52, 964, 100S (1919)
Check Digit Verification of cas no
The CAS Registry Mumber 18747-42-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,7,4 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 18747-42:
(7*1)+(6*8)+(5*7)+(4*4)+(3*7)+(2*4)+(1*2)=137
137 % 10 = 7
So 18747-42-7 is a valid CAS Registry Number.
InChI:InChI=1/C9H17NO/c1-8(11)7-9-5-3-4-6-10(9)2/h9H,3-7H2,1-2H3
18747-42-7Relevant articles and documents
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Leistner et al.
, p. 4040,4043, 4046, 4047 (1973)
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Gupta,Spenser
, p. 1937,1942 (1969)
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ALKALOIDS OF SOME EUROPEAN AND MACARONESIAN SEDOIDEAE AND SEMPERVIVOIDEAE (CRASSULACEAE)
Stevens, Jan F.,Hart, Henk 't,Hendriks, Henk,Malingre, Theo M.
, p. 3917 - 3924 (2007/10/02)
Some 22 pyrrolidine and piperidine alkaloids were detected in the leafy parts of Sedum acre, S. aetnense, S. anglicum, S. brissemoreti, S. farinosum, S. fusiforme, S. lancerottense, S. melanantherum, and S. nudum.In addition to the alkaloids known from S. acre, 1-(2-pyrrolidyl)-propan-2-one and 2-monosubstituted piperidine alkaloids bearing butan-2-one, butan-2-ol, pentan-2-one and pentan-2-ol sidechains were identified.Phenylethylamine was isolated from the vegetative parts of S. album.In S. lydium, S. meyeri-johannis, and 16 species of S. series Rupestria, Aeonium, Greenovia, Jovibarba and Sempervivum no alkaloids could be detected.The results indicate a correlation between the presence of alkaloids and the major evolutionary trends in the European and Macaronesian Crassulaceae. Key Word Index: Sedum; Aeonium; Greenovia; Jovibarba; Sempervivum; Crassulaceae; pyrrolidine and piperidine alkaloids; chemotaxonomy; evolution.
