187592-70-7 Usage
Description
(1S,2R,5R)-2-(1,1-dichloro-2,2,2-trifluoro-ethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-4-one is a complex organic compound with a three-dimensional structure consisting of carbon, hydrogen, oxygen, and chlorine atoms. It features a bicyclic ring system and a ketone functional group, with two chiral centers, resulting in multiple stereoisomers. This synthetic intermediate is utilized in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity also make it a promising candidate for applications in organic synthesis and medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
(1S,2R,5R)-2-(1,1-dichloro-2,2,2-trifluoro-ethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-4-one is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure and reactivity contribute to the creation of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, (1S,2R,5R)-2-(1,1-dichloro-2,2,2-trifluoro-ethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-4-one serves as a key intermediate in the synthesis of agrochemicals. Its properties allow for the development of effective compounds for crop protection and other agricultural applications.
Used in Organic Synthesis:
(1S,2R,5R)-2-(1,1-dichloro-2,2,2-trifluoro-ethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-4-one is utilized in organic synthesis for the preparation of various specialty chemicals. Its complex structure and functional groups make it a valuable building block for creating novel compounds with specific properties and applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (1S,2R,5R)-2-(1,1-dichloro-2,2,2-trifluoro-ethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-4-one is employed for the design and synthesis of new pharmaceutical agents. Its unique structure and reactivity enable the development of innovative molecules with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 187592-70-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,5,9 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 187592-70:
(8*1)+(7*8)+(6*7)+(5*5)+(4*9)+(3*2)+(2*7)+(1*0)=187
187 % 10 = 7
So 187592-70-7 is a valid CAS Registry Number.
187592-70-7Relevant articles and documents
Process for the preparation of cyclopropane carboxylic acids and intermediates therefor
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, (2008/06/13)
The compounds 3-(2,2-dichloro-3,3,3-trifluoro-1-hydroxypropyl)-2,2-dimethyl-(1R,cis)-cyclopropane carboxylic acid, cis-3-(2,2-dichloro-3,3,3-trifluoro-1-hydroxypropyl)-2,2-dimethyl-cyclopropane carboxylic acid and (1R,5S)-4-(1,1-dichloro-2,2,2-trifluoroethyl)-6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one occur as intermediates in a process for the preparation of insecticidally active cyclopropane carboxylate esters, said process starting from 6,6-dimethyl-4-hydroxy-3-oxabicyclo[3.1.0]hexan-2-one (Biocartol) which is reacted with the compound CF3 --CC1X2 (X=halogen) in the presence of zinc.
PRACTICAL AND STEREOCONTROLLED SYNTHESES OF BOTH (1R*,3S*)- AND (1R*,3R*)-3-(2-CHLORO-3,3,3-TRIFLUORO-1-PROPENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATES
Fujita, Makoto,Hiyama, Tamejiro,Kondo, Kiyosi
, p. 2139 - 2142 (2007/10/02)
The title compounds of (1R*,3S*) configuration were prepared from 3-formyl-2,2-dimethylcyclopropanecarboxylate by addition of CF3CCl2ZnCl, acetylation, and reductive β-elimination with zinc, whereas the (1R*,3R*) isomer was derived from Me2C=CHCH(OH)CCl2CF3 by diazoacetylation, Cu(II) catalyzed intramolecular cyclization, and the zinc reduction.
