187728-85-4 Usage
Description
Nateglinide Ethyl Ester is an ethyl ester derivative of the oral hypoglycemic agent Nateglinide, which is used for the treatment of type 2 diabetes. It is a synthetic compound that acts as an insulin secretagogue, helping to lower blood sugar levels by stimulating the release of insulin from the pancreas. However, it has been observed that Nateglinide Ethyl Ester does not have any significant effects on gross behavior in mice.
Uses
Since the provided materials do not specify any particular applications for Nateglinide Ethyl Ester, it is difficult to list its uses. However, based on its parent compound Nateglinide, we can infer that it may have potential applications in the following areas:
Used in Pharmaceutical Industry:
Nateglinide Ethyl Ester could be used as a pharmaceutical agent for the treatment of type 2 diabetes. It may be employed as an insulin secretagogue to help lower blood sugar levels by stimulating the release of insulin from the pancreas.
Used in Research and Development:
Nateglinide Ethyl Ester may be used in research and development for studying its effects on insulin secretion and blood sugar regulation. It could also be used to investigate its potential as a therapeutic agent for diabetes and other related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 187728-85-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,7,2 and 8 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 187728-85:
(8*1)+(7*8)+(6*7)+(5*7)+(4*2)+(3*8)+(2*8)+(1*5)=194
194 % 10 = 4
So 187728-85-4 is a valid CAS Registry Number.
187728-85-4Relevant articles and documents
Green Esterification of Carboxylic Acids Promoted by tert-Butyl Nitrite
Cheng, Xionglve,Jiang, Gangzhong,Li, Xingxing,Tao, Suyan,Wan, Xiaobing,Zhao, Yanwei,Zheng, Yonggao
supporting information, p. 2713 - 2718 (2021/06/25)
In this work, the green esterification of carboxylic acids promoted by tert-butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.
