187979-94-8

Basic information

• Product Name: 5-Benzoyl-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-dihydro-pyrimidine-2,4-dione
• Synonyms: 5-Benzoyl-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-dihydro-pyrimidine-2,4-dione
• CAS NO: 187979-94-8
• Molecular Weight: 348.356
• Mol File: 187979-94-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Benzoyl-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-dihydro-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzoyl-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-dihydro-pyrimidine-2,4-dione(187979-94-8)
• EPA Substance Registry System: 5-Benzoyl-1-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-dihydro-pyrimidine-2,4-dione(187979-94-8)

Safety Data

• Hazardous Substances Data: 187979-94-8(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 187979-95-9 1-[(2R,4S,5R)-4-(tert-Butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-(hydroxy-phenyl-methyl)-5-methyl-dihydro-pyrimidine-2,4-dione 
• 187979-92-6 3′,5′-bis-O-[(tert-butyl)dimethylsilyl]-5,6-dihydrothymidine 
• 5627-00-9 5,6-dihydrothymidine 
• 187979-93-7 5-Benzoyl-1-[(2R,4S,5R)-4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-5-methyl-dihydro-pyrimidine-2,4-dione 

Relevant articles and documents

DNA damage induced via 5,6-dihydrothymid-5-yl in single-stranded oligonucleotides

5,6-Dihydrothymid-5-yl (4) is generated via Norrish type I cleavage of isopropyl ketone 7. Ketone 7 was site specifically incorporated into chemically synthesized polythymidylates and an oligonucleotide containing all four native deoxyribonucleotides. No