187986-17-0

Basic information

• Product Name: WKYMVM
• Synonyms: H-TRP-LYS-TYR-MET-VAL-D-MET-NH2 TRIFLUOROACETATE;WKYMVMAMIDE TRIFLUOROACETATE;WKYMVM;H-Trp-Lys-Tyr-Met-Val-D-Met-NH2;M.W. 856.11 C41H61N9O7S2;Tryptophanyl-lysinyl-tyrosinyl-methionyl-valinyl-D-methionine;Trp-Lys-Tyr-Met-Val-D-Met;WKYMVMaMide, W-Peptide
• CAS NO: 187986-17-0
• Molecular Formula: C41H60N8O8S2
• Molecular Weight: 857.09
• Product Categories: N-Formyl Peptide receptor
• Mol File: 187986-17-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 1269.6 °C at 760 mmHg
• Flash Point: 721.6 °C
• Appearance: white to off-white/
• Density: 1.268 g/cm³
• Storage Temp.: -20°C
• Solubility: H2O: >2mg/mL
• PKA: 9.82±0.15(Predicted)
• CAS DataBase Reference: WKYMVM(CAS DataBase Reference)
• NIST Chemistry Reference: WKYMVM(187986-17-0)
• EPA Substance Registry System: WKYMVM(187986-17-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 187986-17-0(Hazardous Substances Data)

Usage

Description

WKYMVM, also known as a lipoxin A4 receptor agonist, is a compound that specifically targets and activates the orphan monocyte-expressed chemoattractant receptor FPRL2. This interaction plays a crucial role in various biological processes and has potential therapeutic applications.

Uses

Used in Pharmaceutical Applications:
WKYMVM is used as a therapeutic agent for modulating the immune response and inflammation. By targeting the FPRL2 receptor, it can potentially be employed in the treatment of various inflammatory and immune-related disorders.
Used in Research Applications:
In the field of research, WKYMVM serves as a valuable tool for studying the role of the FPRL2 receptor in cellular processes and understanding its involvement in various diseases. This knowledge can contribute to the development of novel therapeutic strategies and drug targets.
Used in Drug Development:
WKYMVM can be utilized in the development of new drugs that target the FPRL2 receptor, potentially leading to the creation of more effective treatments for a range of conditions, including autoimmune diseases and chronic inflammation.
Used in Diagnostic Applications:
WKYMVM may also be employed in the development of diagnostic tools and tests that can identify and monitor the activity of the FPRL2 receptor, aiding in the early detection and assessment of related diseases.

Upstream product

• 92122-45-7 Fmoc-D-Lys(BOC)-OH 
• 71989-28-1 Nα-fluorenyl-9-methoxycarbonyl-D-Met 
• 84624-17-9 N-(9-fluorenylmethoxycarbonyl)-D-valine 
• 118488-18-9 Fmoc-D-Tyr(O-tBu)-OH 
• 163619-04-3 1-tert-butoxycarbonyl-N-[(9-fluorenyl)methoxycarbonyl]-D-tryptophan 
• 33224-01-0 (2S,3S)-1-methyl-5-oxo-2-(pyridin-3-yl)pyrrolidine-3-carboxylic acid 
• 68858-20-8 Fmoc-Val-OH 
• 71989-38-3 Fmoc-Tyr(tBu)-OH 
• 71989-26-9 Fmoc-Lys(tert-butoxycarbonyl) 
• 71989-28-1 N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-methionine 
• 143824-78-6 3-[(S)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]indole-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

COMPLEX IN WHICH ANTI-COTININE ANTIBODY IS BOUND TO CONJUGATE OF COTININE AND BINDING SUBSTANCE, AND USE THEREOF

The present invention relates to a complex in which an anti-cotinine antibody is bound to a conjugate of a binding material and cotinine, and a use of the complex. The complex according to the present invention may be used as an analysis tool in an in vitro biological assay method, and may retain the specific reactivity and the biological function of the binding material, and the capabilities of inducing complement-mediated cell cytotoxicity (CDC) and antibody-dependent cell cytotoxicity (ADCC) and a prolonged in vivo half-life, which are intrinsic characteristics of an antibody.