187996-10-7Relevant articles and documents
Synthesis, NMR spectroscopy study, and antimuscarinic activity of a series of 2-(acyloxymethyl)-1,3-dioxolanes
Malmusi, Luca,Mucci, Adele,Schenetti, Luisa,Gulini, Ugo,Marucci, Gabriella,Brasili, Livio
, p. 2071 - 2080 (2007/10/03)
A series of 19-dioxolane-based ligands, bearing hydroxymethyl or ester functionalities, was synthesized and tested as potential muscarinic antagonists. The compounds display moderate to low affinity for the three receptor subtypes M1-M3/s