188004-30-0Relevant articles and documents
Synthesis of 2-Alkenyl-Tethered Anilines
Denmark, Scott E.,Chi, Hyung Min
, p. 2873 - 2888 (2017)
Three general routes for the synthesis of (E)-2-alkenyl-tethered anilines have been developed. The first route involves a 3-aza-Cope rearrangement of N -allylic anilines in the presence of a Lewis acid. The requisite N -allylic anilines were prepared by t
A study on the regio- and stereoselectivity in palladium-catalyzed cyclizations of alkenes and alkynes bearing bromoaryl and nucleophilic groups
Bruyère, Didier,Bouyssi, Didier,Balme, Geneviève
, p. 4007 - 4017 (2007/10/03)
We have studied the remarkable dependence of the stereochemistry of the cyclization on the double bond geometry and of the effect of the bulkiness of the nucleophile on the regiochemistry of the palladium mediated cyclization of alkenes bearing aryl bromides and nucleophiles. In contrast, the cyclization of the acetylenic homologous substrates is not dependent on the nature of the nucleophile.