188293-26-7

Basic information

• Product Name: C₁₃H₁₅N₅O₃
• Synonyms: C₁₃H₁₅N₅O₃
• CAS NO: 188293-26-7
• Molecular Weight: 289.294
• Mol File: 188293-26-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₅N₅O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₅N₅O₃(188293-26-7)
• EPA Substance Registry System: C₁₃H₁₅N₅O₃(188293-26-7)

Safety Data

• Hazardous Substances Data: 188293-26-7(Hazardous Substances Data)

Upstream product

• 146000-76-2 C₆H₉N₃O₃ 
• 138-89-6 p-dimethylaminonitrosobenzene 

Downstream Products

• 188293-35-8 4-[(Z)-4-Dimethylamino-phenylimino]-3-methyl-5-oxo-4,5-dihydro-pyrazole-1-carboxylic acid amide 
• 188293-39-2 C₁₂H₁₄N₄O₂ 

Relevant articles and documents

Synthesis and reactions of some nitrone derivatives

Arylnitroso compounds easily react as nucleophiles with conjugated azoalkenes to give α-(arylimino-N-oxide)hydrazones by their 1,4-addition to the azo-ene system. These adducts undergo an internal heterocyclization process with pyrazole ring formation to produce 1-alkoxycarbonyl- or 1-aminocarbonyl-3-methyl-4-(arylimino-N-oxide)-1H-pyrazol-5(4H)-ones stereoselectively in Z form by loss of an alcohol molecule. Deoxygenation of these compounds with triphenylphosphine affords 1-alkoxycarbonyl- or 1-aminocarbonyl-3-methyl-4-arylimino-1H-pyrazol-5(4H)-ones. Basic treatment with triethylamine of the same compounds leads to 3-methyl-4-(arylimino-N-oxide)-1H-pyrazol-5(4H)-ones by removal of the substituents on N(1) heteroatom of the pyrazole ring. Both deoxygenation and basic treatment of 1-alkoxycarbonyl- and 1-aminocarbonyl-3-methyl-4-(arylimino-N-oxide)-1H-pyrazol-5(4H)-ones have been realized sequentially, providing 3-methyl-4-arylimino-1H-pyrazol-5(4H)-ones. The same products were successfully obtained by reversing the order of these processes.