188411-47-4Relevant articles and documents
An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups
Perszyk, Riley,Katzman, Brooke M.,Kusumoto, Hirofumi,Kell, Steven A.,Epplin, Matthew P.,Tahirovic, Yesim A.,Moore, Rhonda L.,Menaldino, David,Burger, Pieter,Liotta, Dennis C.,Traynelis, Stephen F.
, (2018/08/28)
N-methyl-D-aspartate receptors (NMDARs) are an important receptor in the brain and have been implicated in multiple neurological disorders. Many non-selective NMDAR-targeting drugs are poorly tolerated, leading to efforts to target NMDAR subtyp
Synthesis of novel tetrahydro-3H-benzothieno[2,3-d]imidazoles
Johnson, Christopher N.,Martin, Roger T.,Morgan, Helen K.A.,Thompson, Mervyn
, p. 473 - 482 (2007/10/03)
The synthesis of novel tetrahydro 3H-benzothieno[2,3-d]imidazole 2b and the corresponding 2-carboxylate 2a is described. Intramolecular cyclisation of a key 1,2-diacylaminobenzothiophene 9 was utilised.
