188476-28-0 Usage
Description
(R)-2-N-(tert-butoxycarbonyl)amino-2-methyl-3-hydroxypropanoic acid methyl ester is a synthetic amino acid derivative featuring a tert-butoxycarbonyl (Boc) protective group. It is characterized by its methyl ester of a hydroxyproline derivative, which includes a methyl and an amino group within its molecular structure. (R)-2-N-(tert-butoxycarbonyl)amino-2-methyl-3-hydroxypropanoic acid methyl ester is recognized for its unique structure and reactivity, making it a promising candidate in the fields of organic synthesis and drug development.
Uses
Used in Organic Synthesis:
(R)-2-N-(tert-butoxycarbonyl)amino-2-methyl-3-hydroxypropanoic acid methyl ester is used as an intermediate in organic synthesis for its unique reactivity and structural properties. The presence of the Boc protective group allows for selective removal under mild conditions, facilitating the synthesis of complex organic molecules.
Used in Drug Development:
In the pharmaceutical industry, (R)-2-N-(tert-butoxycarbonyl)amino-2-methyl-3-hydroxypropanoic acid methyl ester is used as a valuable intermediate in the synthesis of pharmaceutical compounds. Its potential biological activity, stemming from the amino and hydroxy functional groups, makes it a promising candidate for the development of new drugs.
Used in Peptide Synthesis:
(R)-2-N-(tert-butoxycarbonyl)amino-2-methyl-3-hydroxypropanoic acid methyl ester is utilized as a building block in peptide synthesis. The Boc protective group's selective removal under mild conditions ensures the controlled formation of peptide bonds, which is crucial for the synthesis of specific peptide sequences with desired biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 188476-28-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,4,7 and 6 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 188476-28:
(8*1)+(7*8)+(6*8)+(5*4)+(4*7)+(3*6)+(2*2)+(1*8)=190
190 % 10 = 0
So 188476-28-0 is a valid CAS Registry Number.
188476-28-0Relevant articles and documents
Method for producing an optically active homoserine deriv. α-
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Paragraph 0071; 0072; 0073; 0074, (2019/05/25)
PROBLEM TO BE SOLVED: To provide a method for obtaining an optically-active α-alkylserine derivative from a 1,3-propanediol derivative. SOLUTION: The method is provided, which produces an optically-active α-alkylserine derivative, such as (R) or (S)
Stereospecific Synthesis and Biological Evaluation of S/R-[123I]IVAIB for Brain Tumor Imaging
Yu, W.,McConathy, J.,Williams, L.,Malveaux, E.,Camp, V. M.,Zhang, Z.,Olson, J.,Goodman, M. M.
, p. S82 - S82 (2007/10/03)
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