188643-08-5

Basic information

• Product Name: Sulfamide, dimethyl(phenylmethylene)-, (E)-
• CAS NO: 188643-08-5
• Molecular Formula: C9H12N2O2S
• Molecular Weight: 212.272
• Mol File: 188643-08-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Sulfamide, dimethyl(phenylmethylene)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Sulfamide, dimethyl(phenylmethylene)-, (E)-(188643-08-5)
• EPA Substance Registry System: Sulfamide, dimethyl(phenylmethylene)-, (E)-(188643-08-5)

Safety Data

• Hazardous Substances Data: 188643-08-5(Hazardous Substances Data)

Upstream product

• 3984-14-3 N,N-dimethylsulfamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 118876-86-1 1-dimethylsulphamoyl-5-phenylimidazole 
• 4383-23-7 1-phenyl-but-3-enylamine 
• 953385-48-3 N-(2-methyl-1-phenyl-3-butenyl)-N,N-dimethylsulfonamide 

Relevant articles and documents

A copper(II)-catalyzed aza-friedel-crafts reaction of N-(2-Pyridyl)sulfonyl aldimines: Synthesis of unsymmetrical diaryl amines and triaryl methanes

(Chemical Equation Presented) The choice of the (2-pyridyl)sulfonyl moiety as an N-protecting group and Cu(OTf)2/(±)-binap as catalyst system lead to a highly efficient aza-Friedel-Crafts reaction of electron-rich arenes (Ar2-H) and heteroarenes with N-sulfonyl imines. This protocol is also amenable to the synthesis of unsymmetrical triaryl methanes through a second electrophilic aromatic substitution with a different electron-rich arene (Ar3-H; see scheme).