188799-42-0 Usage
General Description
1-Methyl-2-(1-Methyl-1H-imidazol-2-yl)-1H-benzimidazole, also known as Selumetinib, is a chemical compound used in the treatment of certain types of cancer, such as advanced thyroid cancer and non-small cell lung cancer. It works by inhibiting the activity of certain proteins that control the growth and spread of cancer cells. Selumetinib is a promising targeted therapy for cancer treatment, and it is currently being studied in clinical trials for the treatment of other types of cancer as well. It is typically administered orally in the form of a tablet or capsule. Common side effects of selumetinib include diarrhea, nausea, rash, and fatigue.
Check Digit Verification of cas no
The CAS Registry Mumber 188799-42-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,7,9 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 188799-42:
(8*1)+(7*8)+(6*8)+(5*7)+(4*9)+(3*9)+(2*4)+(1*2)=220
220 % 10 = 0
So 188799-42-0 is a valid CAS Registry Number.
188799-42-0Relevant articles and documents
Annulated derivatives of 2,2′-biimidazole, 2-(2′-imidazolyl)benzimidazole, and 2,2′-bibenzimidazole
Ames, James R.,Houghtaling, Melissa A.,Terrian, Deborah L.,Mitchell, Timothy P.
, p. 28 - 36 (1997)
Preparation of bisannulated salts of 2,2′-biimidazole, 2-(2′-imidazolyl)benzimidazole, 2,2′-bibenzimidazole, and annulated salts of 1,1′-dimethyl-2,2′-biimidazole, 1,1′-dimethyl-2-(2′-imidazolyl)benzimidazole, and 1,1′-dimethyl-2,2′-bibenzimidazole is accomplished by direct alkylation of the parent azaheterocycle with excess 1,n-dihaloalkane. Discussions of the product conformations use electronic absorption spectra and NMR. The redox potentials of these salts are measured in DMF and CH3CN, and become increasingly more negative and less reversible as the systems become less planar.
