188884-38-0

Basic information

• Product Name: 3-(6-Benzyloxy-1H-indol-3-yl)-1-methyl-4-[1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione
• CAS NO: 188884-38-0
• Molecular Weight: 970.134
• Mol File: 188884-38-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(6-Benzyloxy-1H-indol-3-yl)-1-methyl-4-[1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(6-Benzyloxy-1H-indol-3-yl)-1-methyl-4-[1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione(188884-38-0)
• EPA Substance Registry System: 3-(6-Benzyloxy-1H-indol-3-yl)-1-methyl-4-[1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-pyrrole-2,5-dione(188884-38-0)

Safety Data

• Hazardous Substances Data: 188884-38-0(Hazardous Substances Data)

Upstream product

• 4291-69-4 2,3,4,6-Tetra-O-benzyl-D-glucopyranose 
• 120-72-9 indole 
• 188884-37-9 6-benzyloxy-3-{1-methyl-2,5-dioxo-4-[1-(3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-2,5-dihydro-1H-pyrrol-3-yl}-indole-1-carboxylic acid tert-butyl ester 
• 15903-94-3 6-benzyloxy-1H-indole 
• 178945-28-3 2,5-dihydro-3-[6-benzyloxy-1-(tert-butyloxycarbonyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione 
• 174574-69-7 4-chloro-3-(1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione 

Downstream Products

• 188884-40-4 12,13-dihydro-10-benzyloxy-13-(2,3,4,6-tetra-O-benzyl-β-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-6-methyl-5,7(6H)-dione 

Relevant articles and documents

Synthesis and biological activities of NB-506 analogues: Effects of the positions of two hydroxyl groups at the indole rings

In the course of a study of 6-N-amino-substituted analogues of NB-506 (1), a more potent anticancer drag, J-109,404 (2), in which the formyl group of NB-506 was replaced with a 1,3-dihydroxypropane group, was reported. A study of further modification in the positions of two hydroxyl groups at the indole rings of 2 resulted in the discovery of a 2,10-dihydroxy analogue, J- 107,088 (3), which is a promising anticancer agent with a broader therapeutic window than J-109,404.