188910-74-9

Basic information

• Product Name: L-Glutamic acid, N-[4-[[(2,4-diamino-1H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]methylamino] benzoyl]-, diethyl ester
• CAS NO: 188910-74-9
• Molecular Formula: C24H31N7O5
• Molecular Weight: 497.554
• Mol File: 188910-74-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Glutamic acid, N-[4-[[(2,4-diamino-1H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]methylamino] benzoyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Glutamic acid, N-[4-[[(2,4-diamino-1H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]methylamino] benzoyl]-, diethyl ester(188910-74-9)
• EPA Substance Registry System: L-Glutamic acid, N-[4-[[(2,4-diamino-1H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]methylamino] benzoyl]-, diethyl ester(188910-74-9)

Safety Data

• Hazardous Substances Data: 188910-74-9(Hazardous Substances Data)

Upstream product

• 188910-67-0 (2,4-Diamino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanol 
• 166047-40-1 2,4-diamino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile 
• 166047-41-2 2,4-diaminopyrrolo<2,3-d>pyrimidine-5-carboxaldehyde 
• 2378-95-2 diethyl N-<4-(methylamino)benzoyl>-L-glutamate 
• 188910-70-5 5-Bromomethyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine 

Relevant articles and documents

Effect of N9-methylation and bridge atom variation on the activity of 5-substituted 2,4-diaminopyrrolo[2,3-d]pyrimidines against dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii

The effect of N9-mathylation and bridge atom variation on inhibitory potency and selectivity of 2,4-diaminopyrrolo[2,3-d]pyrimidines against dihydrofolate reductases (DHFR) was studied. Specifically three nonclassical 2,4-diamino-5-((N-methylan