188957-23-5

Basic information

• Product Name: Cyclohexanol, 1-[[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]ethynyl]-
• CAS NO: 188957-23-5
• Molecular Formula: C20H30O2Si
• Molecular Weight: 330.543
• Mol File: 188957-23-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 1-[[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 1-[[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]ethynyl]-(188957-23-5)
• EPA Substance Registry System: Cyclohexanol, 1-[[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]ethynyl]-(188957-23-5)

Safety Data

• Hazardous Substances Data: 188957-23-5(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 626-02-8 3-Iodophenol 
• 78-27-3 1-Ethynylcyclohexan-1-ol 
• 133910-12-0 (1,1-dimethylethyl)(3-iodophenoxy)dimethylsilane 

Downstream Products

• 188957-35-9 (Z)-2-(3'-hydroxyphenyl)-1-(1''-hydroxycyclohexyl)ethene 
• 188957-29-1 1-{(Z)-2-[3-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-vinyl}-cyclohexanol 

Relevant articles and documents

The synthesis of 8a-methoxy-2H,6H-chromen-6-ones and corresponding 2H-chromenes by a unique process utilising phenolic oxidation

(Z)-1-Hydroxy-3-(3'-hydroxyphenyl)prop-2-enes undergo phenolic oxidation by phenyliodonium diacetate (PIDA) in methanol to give 8a-methoxy-2H,6H-dihydrochromen-6-ones. These are reduced by DIBAL-H to 2-substituted-Δ3,4-chromenes the overall process being a unique heterocyclic synthesis in which the heteroatom is not initially attached to a benzene ring, but is introduced from a side chain. Parallel oxidations using cis-1-hydroxy-3-(3'-hydroxyphenyl)prop-2,3-oxiranes have also been achieved despite the presence of the sensitive oxirane ring.