189107-45-7 Usage
General Description
1-Methyl-1H-indazole-5-carbonitrile is a chemical compound with the formula C9H8N2. It is a nitrile derivative of indazole, a bicyclic heterocycle containing an indole ring fused to a five-membered nitrogen-containing pyrrole ring. 1-Methyl-1H-indazole-5-carbonitrile is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and organic compounds. It is a white solid that is soluble in organic solvents and has a melting point of around 104-106°C. 1-Methyl-1H-indazole-5-carbonitrile plays a crucial role in the production of a wide range of functional materials, making it an important chemical in the field of organic chemistry and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 189107-45-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,1,0 and 7 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 189107-45:
(8*1)+(7*8)+(6*9)+(5*1)+(4*0)+(3*7)+(2*4)+(1*5)=157
157 % 10 = 7
So 189107-45-7 is a valid CAS Registry Number.
189107-45-7Relevant articles and documents
Thrombin inhibitors
-
, (2008/06/13)
Compounds of the invention are useful in inhibiting thrombin and associated thrombotic occlusions having the following structure: or a pharmaceutically acceptable salt thereof, wherein b is NY or O; c is CY2or N; d is CY3or N; e is CY4or N; f is CY5or N; g is CY6or N; Y4, Y5, and Y6are independently hydrogen, C1-4alkyl, or halogen; Y1and Y2are independently hydrogen, C1-4alkyl, C3-7cycloalkyl, halogen, NH2, OH or C1-4alkoxy, and Y3is hydrogen, C1-4alkyl, C3-7cycloalkyl, halogen, —CN, NH2, OH or C1-4alkoxy; A is and W, W1, R1, R3, R4, R5, X and Z are defined in the specification.
Synthesis of 5-cyanoindazole and 1-methyl and 1-aryl-5-cyanoindazoles
Halley, Frank,Sava, Xavier
, p. 1199 - 1207 (2007/10/03)
5-Cyanoindazoles are conveniently prepared in two to three steps from commercially available 5-bromo-2-fluorobenzaldehyde.
